ArticleeLife2023
Mechanisms and functions of respiration-driven gamma oscillations in the primary olfactory cortex.
Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 32 citations in OpenAlex.
- Effects of a respiratory and neurological rehabilitation treatment plan in post Covid-19 affected university students. Randomized clinical study.Chronic respiratory diseaseTrial
- Article
- A reversible rat model of hyposmia affects respiration-linked brain oscillations and behavior.iScience · 2026Article
- Subspace communication in the hippocampal-retrosplenial axis.bioRxiv : the preprint server for biology · 2026Article
- Cardiac, respiratory, and gastric rhythms independently modulate motor corticospinal excitability in humans.PLoS biology · 2025Article
- Global coordination of brain activity by the breathing cycle.Nature reviews. Neuroscience · 2025Review
- Breathing Modulates Network Activity in Frontal Brain Regions during Anxiety.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- A Neural Circuit For Bergamot Essential Oil-Induced Anxiolytic Effects.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- [Application of optogenetic technology in the research on olfactory bulb neural projection from advanced brain regions to regulate olfactory signal processing].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024Review
- Article
- NMDA receptor antagonist high-frequency oscillations are transmitted via bottom-up feedforward processing.Scientific reports · 2024Article
- Dynamic mechanisms that couple the brain and breathing to the external environment.Communications biology · 2024Review
- Enhanced Release Probability without Changes in Synaptic Delay during Analogue-Digital Facilitation.Cells · 2024Article
- Endogenous cannabinoids in the piriform cortex tune olfactory perception.Nature communications · 2024Article
- Neuropsychiatric consequences of COVID-19 related olfactory dysfunction: could non-olfactory cortical-bound inputs from damaged olfactory bulb also contribute to cognitive impairment?Frontiers in neuroscience · 2023Article
- Controlling neuronal assemblies: a fundamental function of respiration-related brain oscillations in neuronal networks.Pflugers Archiv : European journal of physiology · 2023Review
- Camera-based visual feedback learning aid for recovering sense of smell and taste in COVID-19 survivors: a proof-of-concept study.Frontiers in psychology · 2023Article
- Early development of olfactory circuit function.Frontiers in cellular neuroscience · 2023Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gamma oscillations are believed to underlie cognitive processes by shaping the formation of transient neuronal partnerships on a millisecond scale. These oscillations are coupled to the phase of breathing cycles in several brain areas, possibly reflecting local computations driven by sensory inputs sampled at each breath. Here, we investigated the mechanisms and functions of gamma oscillations in the piriform (olfactory) cortex of awake mice to understand their dependence on breathing and how they relate to local spiking activity. Mechanistically, we find that respiration drives gamma oscillations in the piriform cortex, which correlate with local feedback inhibition and result from recurrent connections between local excitatory and inhibitory neuronal populations. Moreover, respiration-driven gamma oscillations are triggered by the activation of mitral/tufted cells in the olfactory bulb and are abolished during ketamine/xylazine anesthesia. Functionally, we demonstrate that they locally segregate neuronal assemblies through a winner-take-all computation leading to sparse odor coding during each breathing cycle. Our results shed new light on the mechanisms of gamma oscillations, bridging computation, cognition, and physiology.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.