Evidence map›Paper›PMID 36806061›Full record

ArticleBMJ open2023

Price and affordability of key essential medicines for children in Sri Lanka, a lower-middle-income country: comparison of two national cross-sectional surveys done 8 years apart.

Shalini Sri Ranganathan, Thiyahiny Sunil Navaratinaraja, Ramasamy Balasubramaniam, Hemantha Beneragama

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Shalini Sri RanganathanPharmacology, University of Colombo, Colombo, Sri Lanka sshalini14@hotmail.com.ORCID 0000-0003-0184-104X
Thiyahiny Sunil NavaratinarajaPharmacology, University of Jaffna, Jaffna, Sri Lanka.
Ramasamy BalasubramaniamMinistry of Healthcare Nutrition and Indigenous Medicine, Colombo, Sri Lanka.
Hemantha BeneragamaMinistry of Healthcare Nutrition and Indigenous Medicine, Colombo, Sri Lanka.
Ministry of Health, Nutrition and Indigenous Medicine · LKUniversity of Colombo · LKUniversity of Jaffna · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the price and affordability of key essential medicines for children in the private sector in Sri Lanka in 2017/2018, and compare the findings with 2009 data.

designNational cross-sectional descriptive survey using the WHO/Health Action International medicine price methodology. SETTING AND

participantsData were collected from a representative sample of 54 private sector pharmacies selected from all 9 provinces in Sri Lanka using a multistage clustered approach. MAIN OUTCOMES: Median price ratio (MPR) and affordability of originator brand (OB) and lowest priced generics (LPG) of 25 key essential medicines for children.

resultsThe median MPR was 2.69 for OBs and 1.45 for LPGs compared with 3.7 and 1.35 in 2009. MPR of OB of all but one (chlorphenamine syrup) were higher than that of the LPG. MPR-OB>5 was observed for ceftriaxone injection, amoxicillin capsule, mebendazole chewable tablet and metronidazole tablet. This was documented in 2009 as well except for amoxicillin capsule. Prices of LPGs of seven medicines (amoxicillin capsule, amoxicillin suspension, clotrimazole cream, mebendazole chewable tablet, metronidazole tablet) were estimated as excessive (MPR ≥2.5) compared with chlorphenamine syrup, clotrimazole topical cream, ibuprofen syrup and paracetamol syrup in 2009. Compared with 2009, MPRs of OBs of 8 medicines and LPGs of 12 medicines were higher in 2017/2018. Compared with 2009, no change in affordability was noted except for asthma, which has been assessed as affordable in 2017/2018. Standard drug therapy for mild lower respiratory tract infections and acute gastroenteritis remained affordable, and treating epilepsy with carbamazepine syrup remained unaffordable.

conclusionEconomic access to key essential medicines for children has not improved in Sri Lanka in the 8 years' time since the initial survey in 2009.

Indexed as

ChlorpheniramineDrugs, EssentialAmoxicillinChildClotrimazoleCross-Sectional StudiesDeveloping CountriesDrugs, GenericHumansMebendazoleMetronidazoleSri LankaAmoxicillinChlorpheniramineClotrimazoleDrugs, EssentialDrugs, GenericMebendazoleMetronidazoleCLINICAL PHARMACOLOGYHEALTH ECONOMICSHealth policy

Identifiers

PMID36806061
PMCPMC9944639
OpenAlexW4321211371

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.