Evidence map›Paper›PMID 36806042›Full record

ArticleBrain informatics2023

Four-way classification of Alzheimer's disease using deep Siamese convolutional neural network with triplet-loss function.

Faizal Hajamohideen, Noushath Shaffi, Mufti Mahmud, Karthikeyan Subramanian, Arwa Al Sariri, Viswan Vimbi, Abdelhamid Abdesselam, Alzheimer’s Disease Neuroimaging Initiative

Abstract read
In one paragraph

Article in Brain informatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Faizal Hajamohideen *College of Computing and Information Sciences, University of Technology and Applied Sciences, Jamia Street, 311, Sohar, Sultanate of Oman.
Noushath Shaffi *College of Computing and Information Sciences, University of Technology and Applied Sciences, Jamia Street, 311, Sohar, Sultanate of Oman.
Mufti MahmudDepartment of Computer Science, Nottingham Trent University, Clifton Lane, NG11 8NS, Nottingham, UK. muftimahmud@gmail.com.
Karthikeyan SubramanianCollege of Computing and Information Sciences, University of Technology and Applied Sciences, Jamia Street, 311, Sohar, Sultanate of Oman.
Arwa Al SaririCollege of Computing and Information Sciences, University of Technology and Applied Sciences, Jamia Street, 311, Sohar, Sultanate of Oman.
Viswan VimbiCollege of Computing and Information Sciences, University of Technology and Applied Sciences, Jamia Street, 311, Sohar, Sultanate of Oman.
Abdelhamid AbdesselamDepartment of Computer Science, Sultan Qaboos University, 123, Muscat, Sultanate of Oman.
Alzheimer’s Disease Neuroimaging Initiative

Funding

Smartphone-Based "Burst" Cognitive AssessmentsP01AG003991 · NIA · WASHINGTON UNIVERSITY · PI JOHN MORRIS · 1985 to 2026
$69.5M
The natural history of AB accumulation in preclinical ADP01AG026276 · NIA · WASHINGTON UNIVERSITY · PI MORRIS, JOHN · 2005 to 2025
$49.5M
Research Education ComponentP30AG066444 · NIA · WASHINGTON UNIVERSITY · PI DAVID M. HOLTZMAN · 2020 to 2026
$28.7M
NIA NIH HHS P01 AG003991NIA NIH HHS P01 AG026276NIA NIH HHS P30 AG066444
6 · The paper itself

Abstract

Alzheimer's disease (AD) is a neurodegenerative disease that causes irreversible damage to several brain regions, including the hippocampus causing impairment in cognition, function, and behaviour. Early diagnosis of the disease will reduce the suffering of the patients and their family members. Towards this aim, in this paper, we propose a Siamese Convolutional Neural Network (SCNN) architecture that employs the triplet-loss function for the representation of input MRI images as k-dimensional embeddings. We used both pre-trained and non-pretrained CNNs to transform images into the embedding space. These embeddings are subsequently used for the 4-way classification of Alzheimer's disease. The model efficacy was tested using the ADNI and OASIS datasets which produced an accuracy of 91.83% and 93.85%, respectively. Furthermore, obtained results are compared with similar methods proposed in the literature.

Indexed as

Alzheimer’s diseaseClassificationMild cognitive impairmentMRISiameseTriplet-loss

Identifiers

PMID36806042
PMCPMC9937523

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.