ReviewSubstance abuse treatment, prevention, and policy2023
Digital interventions for substance use disorders in young people: rapid review.
Review in Substance abuse treatment, prevention, and policy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 36 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Leveraging Artificial Intelligence for Substance Use Prevention Among Adolescents: A Systematic Review of Emerging Evidence.Inquiry : a journal of medical care organization, provision and financingPooled it
- Virtual Reality in Prevention and Treatment of Substance-Related Disorders: A Systematic Review of Randomized Controlled Trials.Clinical psychology & psychotherapyPooled it
- Usage of an App-Based Addiction Prevention Program for German Vocational Students: Secondary Analysis of Data From a Cluster Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
- Wearable Intervention for Alcohol Use Risk and Sleep in Young Adults: A Randomized Clinical Trial.JAMA network open · 2025Trial
- App-Based Addiction Prevention at German Vocational Schools: Implementation and Reach for a Cluster-Randomized Controlled Trial.Prevention science : the official journal of the Society for Prevention Research · 2024Trial
- Digital Interventions to Facilitate Screening, Brief Interventions, and Referral to Treatment for Substance Use Among Adolescents.Child and adolescent psychiatric clinics of North America · 2026Review
- Preliminary effectiveness of theInternet interventions · 2026Article
- Review of the Characteristics of School-Based Integrated Mental Health and Substance Use Prevention Programs for Adolescents Evaluated Through Clinical Trials Between 2016 and 2026.Children (Basel, Switzerland) · 2026Review
- Systematic Review: Culturally Tailored Digital Substance Use Prevention Interventions for Black Adolescents.JAACAP open · 2026Review
- Digital Intervention Components for Preventing and Reducing Substance Use in Adolescents and Emerging Adults: A Comprehensive Scoping Review.Journal of prevention (2022) · 2026Article
- School-Based Alcohol and Tobacco Prevention Strategies: A Scoping Review and the Missing Role of School Nurses.Children (Basel, Switzerland) · 2026Review
- Virtual reality in school-based health promotion: a mixed-methods evaluation of adolescent alcohol, vaping, and other drug use prevention.Health promotion international · 2026Article
- A videogame for perceived risk of harm from opioid misuse in adolescents: a randomized controlled trial.Nature health · 2026Article
- Novel Synthetic Opioids (NSOs) and Their Evolving Crisis: Utilising NPSPharmaceuticals (Basel, Switzerland) · 2025Article
- Economic Impact of an Employer-Sponsored Integrated Digital Intervention Targeting Substance Use Disorders: Return on Investment Analysis.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2025Article
- Pediatric Applications of Digital Therapeutics: Clinical Evidence and Implementation Landscape.Cureus · 2025Review
- Digital Psychosocial Interventions Tailored for People in Opioid Use Disorder Treatment: Scoping Review.Journal of medical Internet research · 2025Article
- Perspectives of treatment providers overseeing substance use disorder treatment among transition-age adults, aged 18-25 years.Journal of substance use and addiction treatment · 2025Article
- A Mobile App (Joint Effort) to Support Cannabis Use Self-Management and Reinforce the Use of Protective Behavioral Strategies: Development Process and Usability Testing.JMIR formative research · 2025Article
- Narrative Review: Revised Principles and Practice Recommendations for Adolescent Substance Use Treatment and Policy.Journal of the American Academy of Child and Adolescent Psychiatry · 2025Review
Corrections and comments
- Erratum issued
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundYoung people are disproportionately more likely than other age groups to use substances. The rise in substance use and related harms, including overdose, during the Covid-19 pandemic has created a critical need for more innovative and accessible substance use interventions. Digital interventions have shown effectiveness and can provide more engaging, less stigmatizing, and accessible interventions that meet the needs of young people. This review provides an overview of recent literature on the nature of recently published digital interventions for young people in terms of technologies used, substances targeted, intended outcomes and theoretical or therapeutic models employed.
methodsRapid review methodology was used to identify and assess the literature on digital interventions for young people. An initial keyword search was conducted using MEDLINE the Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects (DARE), Health Technology Assessment Database (HTA) and PROSPERO for the years 2015-2020, and later updated to December 2021. Following a title/abstract and full-text screening of articles, and consensus decision on study inclusion, the data extraction process proceeded using an extraction grid developed for the study. Data synthesis relied on an adapted conceptual framework by Stockings, et al. that involved a three-level treatment spectrum for youth substance use (prevention, early intervention, and treatment) for any type of substance.
resultsIn total, the review identified 43 articles describing 39 different digital interventions. Most were early interventions (n = 28), followed by prevention interventions (n = 6) and treatment interventions (n = 5). The identified digital technologies included web-based (n = 14), game-based (n = 10), mobile-based (n = 7), and computer-based (n = 5) technologies, and virtual reality (n = 3). Most interventions targeted alcohol use (n = 20) followed by tobacco/nicotine (n = 5), cannabis (n = 2), opioids (n = 2), ketamine (1) and multiple, or any substances (n = 9). Most interventions used a personalized or normative feedback approach and aimed to effect behaviour change as the intended outcome. Interestingly, a harm reduction approach guided only one of the 39 interventions.
conclusionsWhile web-based interventions represented the most common type of technology, more recently developed immersive and interactive technologies such as virtual reality and game-based interventions call for further exploration. Digital interventions focused mainly on alcohol use, reflecting less concern for tobacco, cannabis, co-occurring substance use, and illicit drug use. Specifically, the recent exacerbation in the opioid crisis throughout North American underlines the urgent need for more prevention-oriented digital interventions for opioid use. The uptake of digital interventions among youth also depends on the incorporation of harm reduction approaches.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.