Evidence map›Paper›PMID 36805418›Full record

ArticleJournal of clinical monitoring and computing2023

Point of care transthoracic echocardiography for the prediction of post - spinal anesthesia hypotension in elderly patients with cardiac diseases and left ventricular dysfunction : Inferior vena cava and post-spinal anesthesia hypotension in elderly patients.

Nefeli Moschovaki, Theodosios Saranteas, Elen Spiliotaki, Dimitrios Giannoulis, Dimitrios Anagnostopoulos, Christina Talliou, Orestis Milionis, Panagiotis Briassoulis, Konstantinos Katogiannis, Thomas Papadimos

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Journal of clinical monitoring and computing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06206434 (Point of Care Ultrasound and Fluids Co-loading for the Prevention of Spinal-induced Hypotension in Dehydrated Elderly Patients and Cardiac Diseases), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06206434 completednot on this mapstarted 2024, after this paper: background citation

Point of Care Ultrasound and Fluids Co-loading for the Prevention of Spinal-induced Hypotension in Dehydrated Elderly Patients and Cardiac Diseases

TypeobservationalSponsorAttikon HospitalRan2024 to 2026Enrolled60ConditionsFluid Therapy, DehydrationArmsPoint of care ultrasonography
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Nefeli MoschovakiSecond Department of Anesthesiology, Medical School, National and Kapodistrian University of Athens, 23 Agnoston Iroon str, 15349, Athens, EU, Greece. nefelimos91@gmail.com.
Theodosios SaranteasSecond Department of Anesthesiology, Medical School, National and Kapodistrian University of Athens, 23 Agnoston Iroon str, 15349, Athens, EU, Greece.
Elen SpiliotakiSecond Department of Anesthesiology, Medical School, National and Kapodistrian University of Athens, 23 Agnoston Iroon str, 15349, Athens, EU, Greece.
Dimitrios GiannoulisSecond Department of Anesthesiology, Medical School, National and Kapodistrian University of Athens, 23 Agnoston Iroon str, 15349, Athens, EU, Greece.
Dimitrios AnagnostopoulosSecond Department of Anesthesiology, Medical School, National and Kapodistrian University of Athens, 23 Agnoston Iroon str, 15349, Athens, EU, Greece.
Christina TalliouSecond Department of Anesthesiology, Medical School, National and Kapodistrian University of Athens, 23 Agnoston Iroon str, 15349, Athens, EU, Greece.
Orestis MilionisSecond Department of Anesthesiology, Medical School, National and Kapodistrian University of Athens, 23 Agnoston Iroon str, 15349, Athens, EU, Greece.
Panagiotis BriassoulisSecond Department of Anesthesiology, Medical School, National and Kapodistrian University of Athens, 23 Agnoston Iroon str, 15349, Athens, EU, Greece.
Konstantinos KatogiannisSecond Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Athens, EU, Greece.
Thomas PapadimosSecond Department of Anesthesiology, Medical School, National and Kapodistrian University of Athens, 23 Agnoston Iroon str, 15349, Athens, EU, Greece.
National and Kapodistrian University of Athens · GRThe Ohio State University Wexner Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In elderly patients with cardiac diseases, changes in cardiovascular physiology diminish cardiovascular reserve and predispose to hemodynamic instability after spinal anesthesia; hence, such patients could be at risk of postoperative complications. Additionally, transthoracic echocardiography (TTE) is used in clinical practice to evaluate cardiovascular hemodynamics. Therefore, we hypothesized that echocardiographic measurements could display significant diagnostic power in the prediction of post - spinal anesthesia hypotension in elderly patients with cardiac diseases and reduced left ventricular ejection fraction (LV-EF). Therefore, sixty-one elderly orthopedic-trauma patients were recruited. Prior to spinal anesthesia a TTE examination was performed. The LV-EF, the stroke volume index (SVI), the peripheral vascular resistance (PVR), the LV filling pressures (E/Em ratio), the right ventricular function [tricuspid annular plane systolic excursion (TAPSE), tricuspid annular systolic velocity (TASV) and fractional area change (FAC)], as well as inferior vena cava (IVC) measurements, such as IVCCI (collapsibility index of the IVC) and dIVCmax (maximum diameter of IVC)-to-IVCCI ratio were assessed. Twenty-six out of sixty-one patients manifested hypotension. Preoperative dIVCmax-to-IVCCI ratio demonstrated the greatest performance amongst echocardiographic indices in predicting post - spinal anesthesia hypotension. The dIVCmax-to-IVCCI ratio < 48 had significantly higher diagnostic power than IVCCI > 0.28, FAC > 42, E/Em ratio < 9 and SVI < 32 (receiver operator characteristic curve analysis). The gray zone for the dIVCmax-to-IVCCI ratio (40-49) showed the lowest number of inconclusive measurements among echocardiographic variables. The preoperative dIVCmax-to-IVCCI ratio could be a reliable echocardiographic index to predict post - spinal anesthesia hypotension in elderly patients with left ventricular dysfunction.

Indexed as

Anesthesia, SpinalHeart DiseasesHypotensionVentricular Dysfunction, LeftAgedEchocardiographyHumansPoint-of-Care SystemsProspective StudiesStroke VolumeVena Cava, InferiorVentricular Function, LeftEchocardiographyInferior vena cavaPost - spinal anesthesia hypotension

Identifiers

PMID36805418
PMCPMC10519869
OpenAlexW4321435760

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.