Evidence map›Paper›PMID 36805196›Full record

ArticleAquatic toxicology (Amsterdam, Netherlands)2023

Initial assessment of the toxicologic effects of leachates from 3-dimensional (3-D) printed objects on sperm quality in two model fish species.

Matthew J Schwing, Yue Liu, Jorge A Belgodere, William T Monroe, Terrence R Tiersch, Ahmed Abdelmoneim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aquatic toxicology (Amsterdam, Netherlands), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matthew J SchwingDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Skip Bertman Drive, Baton Rouge, LA 70803, USA.
Yue LiuAquatic Germplasm and Genetic Resources Center, Louisiana State University Agricultural Center, Baton Rouge, LA 70820, USA.
Jorge A BelgodereDepartment of Biological and Agricultural Engineering, College of Engineering, Louisiana State University, Baton Rouge, LA 70803, USA.
William T MonroeDepartment of Biological and Agricultural Engineering, College of Engineering, Louisiana State University, Baton Rouge, LA 70803, USA.
Terrence R TierschAquatic Germplasm and Genetic Resources Center, Louisiana State University Agricultural Center, Baton Rouge, LA 70820, USA.
Ahmed AbdelmoneimDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Skip Bertman Drive, Baton Rouge, LA 70803, USA. Electronic address: aahmed10@lsu.edu.

Funding

Safeguarding Genetic Resources of Aquatic Biomedical Models - Research SupplementalR24OD028443 · OD · LOUISIANA STATE UNIV AGRICULTURAL CENTER · PI Jack Koch, Yue Liu · 2020 to 2026
$5.4M
Development of Germplasm Resources for Preservation of Aquatic ModelsR24OD010441 · OD · LOUISIANA STATE UNIV AGRICULTURAL CENTER · PI BLACKBURN, HARVEY D., MONROE, WILLIAM · 2012 to 2021
$4.3M
NIH HHS R24 OD010441NIH HHS R24 OD028443
6 · The paper itself

Abstract

The use of 3-dimensional (3-D) printing is gaining popularity in life sciences and driving innovation in fields including aquatic sperm cryopreservation. Yet, little is known about the effects leachates from these objects may have on biological systems. In this study, we investigated if exposure to leachates from 3-D printed objects fabricated from different photo-curable resins could affect sperm quality in two model fish species, zebrafish (Danio rerio) and goldfish (Carassius auratus). Leachates were collected following contact periods of 10 min and 22 h with objects manufactured using a mask LCD resin printer and three different commercially available resins (i.e., standard, eco-friendly, and impact-resistant). Sperm cells were exposed to the leachates for 18 min, and parameters related to sperm motility, cell count, and membrane integrity were evaluated. All experiments were blinded. Leachate originating from contact with impact-resistant resin for 10 min significantly reduced the cell count of zebrafish sperm, while leachate originating from contact with standard resin for 22 h significantly increased the beat cross frequency of goldfish sperm. The changes were not observed across species and no adverse effects were recorded in percent motility, velocity, amplitude of lateral head movement, or membrane integrity of sperm. Our findings demonstrate that exposure to leachates from certain 3-D printed resins can affect sperm quality, while other resins may support sperm quality evaluation. Further investigations are warranted to assess other parameters, effects, and their biological relevance for a variety of aquatic species.

Indexed as

Water Pollutants, ChemicalZebrafishAnimalsGoldfishMaleSemenSpermatozoaSperm MotilityWater Pollutants, Chemical3-D printingFish spermLeachateSperm qualityToxicity

Identifiers

PMID36805196
PMCPMC9993348

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.