ArticleNature plants2023
Tight genetic linkage of genes causing hybrid necrosis and pollinator isolation between young species.
Article in Nature plants, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- The molecular evolutionary basis of species formation revisited.Trends in genetics : TIG · 2025Review
- Evolution of petal patterning: blooming floral diversity at the microscale.The New phytologist · 2025Review
- The GenusPlants (Basel, Switzerland) · 2025Article
- Genetic Cause of Hybrid Lethality Observed in Reciprocal Interspecific Crosses betweenInternational journal of molecular sciences · 2024Article
- Shades of white: The Petunia long corolla tube clade evolutionary history.Genetics and molecular biology · 2024Article
- How the switch to hummingbird pollination has greatly contributed to our understanding of evolutionary processes.The New phytologist · 2024Review
- Maximization through optimization? On the relationship between hybrid performance and parental genetic distance.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 4 countries.
Funding
Abstract
The mechanisms of reproductive isolation that cause phenotypic diversification and eventually speciation are a major topic of evolutionary research. Hybrid necrosis is a post-zygotic isolation mechanism in which cell death develops in the absence of pathogens. It is often due to the incompatibility between proteins from two parents. Here we describe a unique case of hybrid necrosis due to an incompatibility between loci on chromosomes 2 and 7 between two pollinator-isolated Petunia species. Typical immune responses as well as endoplasmic reticulum stress responses are induced in the necrotic line. The locus on chromosome 2 encodes ChiA1, a bifunctional GH18 chitinase/lysozyme. The enzymatic activity of ChiA1 is dispensable for the development of necrosis. We propose that the extremely high expression of ChiA1 involves a positive feedback loop between the loci on chromosomes 2 and 7. ChiA1 is tightly linked to major genes involved in the adaptation to different pollinators, a form of pre-zygotic isolation. This linkage of pre- and post-zygotic barriers strengthens reproductive isolation and probably contributes to rapid diversification and speciation.
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