Evidence map›Paper›PMID 36805031›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2023

Hypertensive emergencies and urgencies: a preliminary report of the ongoing Italian multicentric study ERIDANO.

Fabrizio Vallelonga, Marco Cesareo, Leonardo Menon, Dario Leone, Enrico Lupia, Fulvio Morello, Silvia Totaro, Carlo Aggiusti, Massimo Salvetti, Antonella Ioverno and 9 more

Abstract readMulticenter Study
In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Observational
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Preliminary results of an ongoing multicentric prospective study on hypertensive emergencies and urgencies in Italy.Hypertension research : official journal of the Japanese Society of Hypertension · 2023
    Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Fabrizio Vallelonga *Division of Internal Medicine, Hypertension Unit, Città della Salute e della Scienza Hospital, Department of Medical Sciences, University of Turin, Turin, Italy. vallelonga.fabrizio@gmail.com.
Marco Cesareo *Division of Internal Medicine, Hypertension Unit, Città della Salute e della Scienza Hospital, Department of Medical Sciences, University of Turin, Turin, Italy.
Leonardo MenonDivision of Internal Medicine, Hypertension Unit, Città della Salute e della Scienza Hospital, Department of Medical Sciences, University of Turin, Turin, Italy.
Dario LeoneDivision of Internal Medicine, Hypertension Unit, Città della Salute e della Scienza Hospital, Department of Medical Sciences, University of Turin, Turin, Italy.
Enrico LupiaEmergency Medicine Unit, Città della Salute e della Scienza Hospital, Department of Medical Sciences, University of Turin, Turin, Italy.
Fulvio MorelloEmergency Medicine Unit, Città della Salute e della Scienza Hospital, Department of Medical Sciences, University of Turin, Turin, Italy.
Silvia TotaroEmergency Medicine Unit, Città della Salute e della Scienza Hospital, Department of Medical Sciences, University of Turin, Turin, Italy.
Carlo AggiustiDepartment of Internal Medicine, ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy.
Massimo SalvettiDepartment of Internal Medicine, ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy.
Antonella IovernoClinic of Emergency Medicine, Department of Internal Medicine, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.
Alessandro MalobertiCardiothoracovascular Department, Cardiology 4 Unit, Grande Ospedale Metropolitano Niguarda Ca Granda, University of Milan-Bicocca, Milan, Italy.
Ilaria FucileDepartment of Advanced Biomedical Science, Hypertension Research Center, "Federico II" University Hospital of Naples, Naples, Italy.
Franco CipolliniDepartment of Medical Specialties, AUSL Toscana Centro, Internal Medicine Unit, San Marcello e San Jacopo I Hospital, Pistoia, Italy.
Nicola NestiDepartment of Medical Specialties, AUSL Toscana Centro, Internal Medicine Unit, San Marcello e San Jacopo I Hospital, Pistoia, Italy.
Costantino MancusiDepartment of Advanced Biomedical Science, Hypertension Research Center, "Federico II" University Hospital of Naples, Naples, Italy.
Aldo PendeClinic of Emergency Medicine, Department of Internal Medicine, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.
Cristina GiannattasioCardiothoracovascular Department, Cardiology 4 Unit, Grande Ospedale Metropolitano Niguarda Ca Granda, University of Milan-Bicocca, Milan, Italy.
Maria Lorenza MuiesanDepartment of Internal Medicine, ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy.
Alberto MilanDivision of Internal Medicine, Hypertension Unit, Città della Salute e della Scienza Hospital, Department of Medical Sciences, University of Turin, Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertensive urgencies (HU) and hypertensive emergencies (HE) are challenges for the Emergency Department (ED). A prospective multicentre study is ongoing to characterize patients with acute hypertensive disorders, prevalence of subclinical hypertension-mediated organ damage (HMOD), short- and long-term prognosis; this is a preliminary report. Patients admitted to the ED with symptomatic blood pressure (BP) ≥180/110 mmHg were enrolled. They were managed by ED personnel according to their clinical presentations. Subsequently they underwent clinical evaluation and subclinical HMOD assessment at a Hypertension Centre within 72 h from enrolment. 122 patients were included in this report. Mean age was 60.7±13.9 years, 52.5% were females. 18 (14.8%) patients were diagnosed with HE, 108 (88.5%) with HU. There were no differences in gender, BMI, and cardiovascular comorbidities between groups. At ED discharge, 66.7% and 93.6% (p = 0.003) of HE and HU patients, respectively, had BP < 180/110 mmHg. After 72 h, 34.4% of patients resulted normotensive; 35.2%, 22.1%, and 8.2% had hypertension grade 1, 2, and 3, respectively. Patients with uncontrolled BP at office evaluation had higher vascular HMOD (49.1 vs. 25.9%, p = 0.045). Cardiac (60 vs. 34%, p = 0.049), renal (27.8 vs. 9.6%, p = 0.010) and cerebral (100 vs. 21%, p < 0.001) HMOD was more frequent in HE compared to HU group. HE showed greater cardiac, renal, and cerebral subclinical HMOD, compared to HU. 72-hours BP control is not associated with different HMOD, except for vascular HMOD; therefore, proper comprehensive examination after discharge from the ED could provide added value in cardiovascular risk stratification of such patients. One third of patients with acute blood pressure rise evaluated to the ED resulted normotensive at office evaluation (<72 hours after discharge). Patients with hypertensive emergency showed greater cardiac, renal, and cerebral subclinical HMOD, compared to the patients with hypertensive urgency. BP: blood pressure; HMOD: hypertension-mediated organ damage; y.o.: years old; mo.: months.

Indexed as

HypertensionHypertension, MalignantAgedBlood PressureEmergenciesFemaleHumansItalyMaleMiddle AgedProspective Studiesemergency departmenthypertension mediated organ damagehypertensive emergencieshypertensive urgenciesshort-term blood pressure control

Identifiers

PMID36805031
PMCPMC9940066

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.