Evidence map›Paper›PMID 36804921›Full record

ReviewSeminars in fetal & neonatal medicine2023

Vaccination and treatment options for SARS-CoV2 infection affecting lactation and breastfeeding.

Melissa J Chen, Ritu Cheema, Adrienne Hoyt-Austin, Alicia Agnoli, Kara Kuhn-Riordon, Laura R Kair

Open access · hybridAbstract readReview
In one paragraph

Review in Seminars in fetal & neonatal medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Clinical features of neonatal COVID-19.Seminars in fetal & neonatal medicine · 2023
    Review
  4. Maternal and perinatal COVID-19 - The past, present and the future.Seminars in fetal & neonatal medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Melissa J ChenDepartment of Obstetrics and Gynecology, University of California, Davis, 4860 Y Street, Suite 2500, Sacramento, CA, 95817, USA. Electronic address: mejchen@ucdavis.edu.
Ritu CheemaDivision of Pediatric Infectious Diseases, Department of Pediatrics, University of California, School of Medicine, UC Davis Children's Hospital, 2315 Stockton Blvd, Sacramento, CA, 95817, USA. Electronic address: ritcheema@ucdavis.edu.
Adrienne Hoyt-AustinDivision of General Pediatrics, Department of Pediatrics, 2516 Stockton Blvd, Ticon II, Sacramento, CA, 95817, USA. Electronic address: aehoyt@ucdavis.edu.
Alicia AgnoliDepartment of Family and Community Medicine, 4860 Y Street, Suite 1600, Sacramento, CA, 95817, USA. Electronic address: aagnoli@ucdavis.edu.
Kara Kuhn-RiordonDivision of Neonatology, Department of Pediatrics, 2516 Stockton Blvd, Sacramento, CA, 95817, USA. Electronic address: kmkuhn@ucdavis.edu.
Laura R KairDepartment of Pediatrics, 2521 Stockton Blvd, Sacramento, CA, 95817, USA. Electronic address: lrkair@ucdavis.edu.
University of the Pacific · USCalifornia Community Colleges System · USUC Davis Children's Hospital · USUniversity of California, Davis · USUniversity of California System · US

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
Building Interdisciplinary Research Careers in Womens Health at UC Davis - Administrative SupplementK12HD051958 · NICHD · UNIVERSITY OF CALIFORNIA DAVIS · PI LANE, NANCY E · 2005 to 2023
$9.6M
Telemedicine Consultations to Improve Care Quality of Pediatric Hospital-to-Hospital TransfersK23HD101550 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ROSENTHAL, JENNIFER · 2020 to 2023
$803k
NCATS NIH HHS UL1 TR001860NICHD NIH HHS K12 HD051958NICHD NIH HHS K23 HD101550
6 · The paper itself

Abstract

The COVID-19 pandemic has posed considerable challenges to the health of lactating individuals. Vaccination remains one of the most important strategies for prevention of moderate to severe COVID-19 infection and is associated with protective benefits for lactating individuals and their breastfed infants with overall mild side effects. The current recommendations for COVID-19 treatment in lactating individuals includes remdesivir and dexamethasone for hospitalized patients and Paxlovid® (nirmatrelavir + ritonavir) as outpatient treatment in those with mild disease. As the pandemic continues to evolve with new COVID-19 variants, alternative therapeutic options are potentially needed, and it is critical to include lactating individuals in research to evaluate the safety and efficacy of COVID-19 treatment options in this population.

Indexed as

Breast FeedingCOVID-19COVID-19 Drug TreatmentDrug CombinationsFemaleHumansInfantLactamsLactationLeucineNitrilesPandemicsProlineRitonavirRNA, ViralSARS-CoV-2Drug CombinationsLactamsLeucinenirmatrelvir and ritonavir drug combinationNitrilesProlineRitonavirRNA, ViralBreastfeedingCOVID-19LactationSARS-CoV2TherapeuticsVaccination

Identifiers

PMID36804921
PMCPMC9924042
OpenAlexW4320487129

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.