Evidence map›Paper›PMID 36804566›Full record

ArticlePreventive medicine2023

Cumulative life-course victimization and inflammation in a U.S. national sample: Comparing intersections based on sexual orientation, gender, race/ethnicity, and education.

Aura Ankita Mishra, Carolyn T Halpern, Laura M Schwab-Reese, Kathleen Mullan Harris

Open access · hybridAbstract read
In one paragraph

Article in Preventive medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Aura Ankita MishraCarolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America. Electronic address: auram@email.unc.edu.
Carolyn T HalpernCarolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America; Department of Maternal and Child Health, Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
Laura M Schwab-ReeseDepartment of Public Health, Purdue University, West Lafayette, IN, United States of America.
Kathleen Mullan HarrisCarolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America; Department of Sociology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
University of North Carolina at Chapel Hill · USPurdue University West Lafayette · US

Funding

Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
National Longitudinal Study of Adolescent to Adult Health (Add Health): Wave VII Core ProjectU01AG071448 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Allison E Aiello, Lauren M Gaydosh · 2021 to 2026
$40.2M
National Longitudinal Study of Adolescent to Adult Health (Add Health): Wave VI Cognition and Early Risk Factors for Dementia ProjectU01AG071450 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI AIELLO, ALLISON E, HUMMER, ROBERT A · 2021 to 2025
$16.2M
Carolina Population CenterR24HD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, SAMUEL PHILIP · 2005 to 2014
$10.0M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
From Biological to Social Processes: Interdisciplinary Training in Life Course ResearchT32HD091058 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROBERT A HUMMER, Amanda L Thompson · 2017 to 2026
$4.3M
Sexual Orientation/Gender Identity, Socioeconomic Status, and Health across the Life CourseR01HD087365 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CONRON, KERITH JANE, HALPERN, CAROLYN T · 2017 to 2021
$3.3M
Differential impacts of co-occurring childhood maltreatment and long-term poly-victimization on chronic physical illnesses via inflammation: Do age at exposure and sexual orientation matter?F32HD103400 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MISHRA, AURA ANKITA · 2020 to 2022
$192k
NIA NIH HHS U01 AG071448NIA NIH HHS U01 AG071450NICHD NIH HHS F32 HD103400NICHD NIH HHS P01 HD031921NICHD NIH HHS P2C HD050924NICHD NIH HHS R01 HD087365NICHD NIH HHS R24 HD050924NICHD NIH HHS T32 HD091058
6 · The paper itself

Abstract

Violence victimization has been associated with low-grade inflammation. Lesbian, Gay, and Bisexual (LGB) individuals are at greater risk for victimization in childhood and young adulthood compared to heterosexuals. Moreover, the intersection of LGB identity with gender, race/ethnicity, and educational attainment may be differentially associated with victimization rates. However, no previous study has examined the role of cumulative life-course victimization during childhood and young adulthood in the association between 1) LGB identity and low-grade inflammation during the transition to midlife, and 2) intersection of LGB identity with gender, race/ethnicity, and educational attainment and low-grade inflammation during the transition to midlife. We utilized multi-wave data from a national sample of adults entering midlife in the United States- the National Longitudinal Study of Adolescent to Adult Health (Add Health; n = 4573) - and tested four bootstrapped mediation models. Results indicate LGB identity, LGB and White, and LGB and Black identities were indirectly associated with low-grade inflammation during the transition to midlife via higher levels of cumulative life-course victimization. Moreover, among LGB adults, the association between 1) less than college education and 2) some college education, and low-grade inflammation was mediated by cumulative life-course victimization. For LGB females, there was a direct association between identity and low-grade inflammation and this association was mediated by cumulative life-course victimization . Reducing accumulation of victimization could be critical for preventing biological dysregulation and disease onset among LGB individuals, particularly for those with multiple marginalized identities.

Indexed as

Crime VictimsSexual and Gender MinoritiesAdolescentAdultEducational StatusEthnicityFemaleHumansInflammationLongitudinal StudiesMaleSexual BehaviorUnited StatesYoung AdultInflammationIntersectionalitySexual minorityViolence victimization

Identifiers

PMID36804566
PMCPMC10068961
OpenAlexW4321350723

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.