Evidence map›Paper›PMID 36804422›Full record

ArticleNeuroImage2023

Evaluating increases in sensitivity from NORDIC for diverse fMRI acquisition strategies.

Logan T Dowdle, Luca Vizioli, Steen Moeller, Mehmet Akçakaya, Cheryl Olman, Geoffrey Ghose, Essa Yacoub, Kâmil Uğurbil

Registry-linked trialAbstract read
In one paragraph

Article in NeuroImage, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07024875 (Precision Neuroimaging of Parkinson's Disease), which is not on this map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07024875 recruitingnot on this mapstarted 2025, after this paper: background citation

Precision Neuroimaging of Parkinson's Disease

Typeobservational_patient_registrySponsorWashington University School of MedicineRan2025 to 2031Enrolled120ConditionsParkinsons Disease (PD)
3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Precision functional imaging in infants using multi-echo fMRI at 7T.bioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Article
  11. Robust-tedana: An automated denoising pipeline for multi-echo fMRI data.bioRxiv : the preprint server for biology · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Principles of intensive human neuroimaging.Trends in neurosciences · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Logan T DowdleCenter for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, 2021 6th Street SE, MN 55455, United States; Department of Neuroscience, University of Minnesota, Minneapolis, MN, United States. Electronic address: dowdl016@umn.edu.
Luca VizioliCenter for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, 2021 6th Street SE, MN 55455, United States.
Steen MoellerCenter for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, 2021 6th Street SE, MN 55455, United States.
Mehmet AkçakayaCenter for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, 2021 6th Street SE, MN 55455, United States; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, United States.
Cheryl OlmanCenter for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, 2021 6th Street SE, MN 55455, United States; Department of Psychology, University of Minnesota, Minneapolis, MN, United States.
Geoffrey GhoseCenter for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, 2021 6th Street SE, MN 55455, United States; Department of Neuroscience, University of Minnesota, Minneapolis, MN, United States; Department of Psychology, University of Minnesota, Minneapolis, MN, United States.
Essa YacoubCenter for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, 2021 6th Street SE, MN 55455, United States.
Kâmil UğurbilCenter for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, 2021 6th Street SE, MN 55455, United States.

Funding

TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Gregory John Metzger, KAMIL UGURBIL · 2019 to 2026
$11.7M
Elementary Neuronal Ensembles to Whole Brain Networks: Ultrahigh Resolution Imaging of Function and Connectivity in Humans - SUPPLEMENTU01EB025144 · NIBIB · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2017 to 2022
$9.7M
Institutional Center Cores for Advanced NeuroimagingP30NS076408 · NINDS · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2020
$4.2M
Linking neuronal, metabolic, and hemodynamic responses across scalesRF1MH117015 · NIMH · UNIVERSITY OF MINNESOTA · PI GHOSE, GEOFFREY M · 2018 to 2018
$3.6M
The Neuronal Underpinnings of Non-invasive Laminar fMRIRF1MH116978 · NIMH · UNIVERSITY OF MINNESOTA · PI DEVINSKY, ORRIN, YACOUB, ESSA · 2018 to 2018
$2.9M
NIBIB NIH HHS P41 EB027061NIBIB NIH HHS U01 EB025144NIMH NIH HHS RF1 MH116978NIMH NIH HHS RF1 MH117015NINDS NIH HHS P30 NS076408
6 · The paper itself

Abstract

As the neuroimaging field moves towards detecting smaller effects at higher spatial resolutions, and faster sampling rates, there is increased attention given to the deleterious contribution of unstructured, thermal noise. Here, we critically evaluate the performance of a recently developed reconstruction method, termed NORDIC, for suppressing thermal noise using datasets acquired with various field strengths, voxel sizes, sampling rates, and task designs. Following minimal preprocessing, statistical activation (t-values) of NORDIC processed data was compared to the results obtained with alternative denoising methods. Additionally, we examined the consistency of the estimates of task responses at the single-voxel, single run level, using a finite impulse response (FIR) model. To examine the potential impact on effective image resolution, the overall smoothness of the data processed with different methods was estimated. Finally, to determine if NORDIC alters or removes temporal information important for modeling responses, we employed an exhaustive leave-p-out cross validation approach, using FIR task responses to predict held out timeseries, quantified using R

Indexed as

Functional NeuroimagingMagnetic Resonance ImagingHumansImage Processing, Computer-AssistedResearch Design

Identifiers

PMID36804422
PMCPMC10234612

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.