ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2023
Oral administration of the commensal Alistipes onderdonkii prolongs allograft survival.
Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed.
- Article
- Article
- The role of theFrontiers in microbiology · 2026Review
- Comparing alignment and de-novo approaches for gut microbiota metagenomic data analysis reveals differences in taxonomic resolution and novel functional insights.Scientific reports · 2025Article
- Alistipes putredinis CCUG 45780BMC microbiology · 2025Article
- Article
- The radioprotective role of human Alistipes onderdonkii identified by multi-omic analysis in patients with prostate cancer.Discover oncology · 2025Article
- Does schistosome infection affect behavior through the gut-brain axis?PLoS neglected tropical diseases · 2025Article
- Delivery of butyrate to the lower gut by polymeric micelles prolongs survival of distal skin allografts.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025Article
- The human gut microbiome and sleep across adulthood: associations and therapeutic potential.Letters in applied microbiology · 2025Review
- Coordinated elimination of bacterial taxa optimally attenuates alloimmunity and prolongs allograft survival.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024Article
- Effect of green banana and pineapple fibre powder consumption on host gut microbiome.Frontiers in nutrition · 2024Article
- Contribution of tryptophan and its metabolites to transplant outcome: a mini-review.Frontiers in immunology · 2024Review
- Macronutrient balance determines the human gut microbiome eubiosis: insights fromFrontiers in microbiology · 2024Article
- Microbiota-dependent and -independent effects of obesity on transplant rejection and hyperglycemia.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Intestinal commensals can exert immunomodulatory effects on the host, with beneficial or detrimental consequences depending on underlying diseases. We have previously correlated longer survival of minor mismatched skin grafts in mice with the presence of an intestinal commensal bacterium, Alistipes onderdonkii. In this study, we investigated its sufficiency and mechanism of action. Oral administration of A onderdonkii strain DSM19147 but not DSM108265 was sufficient to prolong minor mismatched skin graft survival through inhibition of tumor necrosis factor production. Through metabolomic and metagenomic comparisons between DSM19147 and DSM108265, we identified candidate gene products associated with the anti-inflammatory effect of DSM19147. A onderdonkii DSM19147 can lower inflammation both at a steady state and after transplantation and may serve as an anti-inflammatory probiotic beneficial for transplant recipients.
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Registered trials
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