ArticleJournal of orthopaedic surgery and research2023
Design and performance analysis of 3D-printed stiffness gradient femoral scaffold.
Article in Journal of orthopaedic surgery and research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Data-driven multiscale design of composite biomaterials: Integrating experiments, imaging, and computational modeling for biomedical engineering.Materials today. Bio · 2026Review
- Mechanical and biological properties of trabecula and strut scaffolds in bone defect reconstruction.BMC biotechnology · 2026Article
- Patient-Specific Lattice Implants for Segmental Femoral and Tibial Reconstruction (Part 2): CT-Based Personalization, Design Workflows and Validation-A Review.Biomimetics (Basel, Switzerland) · 2026Review
- Patient-Specific Lattice Implants for Segmental Femoral and Tibial Reconstruction (Part 1): Defect Patterns, Fixation Strategies and Reconstruction Options-A Review.Biomimetics (Basel, Switzerland) · 2026Review
- A review of 3D printed medical implant design.3D printing in medicine · 2026Article
- Design and performance analysis of bionic trabecular bone scaffold structure based on Voronoi.Journal of biological engineering · 2025Article
- Integrating Additive and Traditional Manufacturing for Multiscale Bone Tissue Engineering Scaffolds.Journal of functional biomaterials · 2025Review
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Authors and funding
8 authors.
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Abstract
Studies on 3D-printed porous bone scaffolds mostly focus on materials or structural parameters, while the repair of large femoral defects needs to select appropriate structural parameters according to the needs of different parts. In this paper, a kind of stiffness gradient scaffold design idea is proposed. Different structures are selected according to the different functions of different parts of the scaffold. At the same time, an integrated fixation device is designed to fix the scaffold. Finite element method was used to analyze the stress and strain of homogeneous scaffolds and the stiffness gradient scaffolds, and the relative displacement and stress between stiffness gradient scaffolds and bone in the case of integrated fixation and steel plate fixation. The results showed that the stress distribution of the stiffness gradient scaffolds was more uniform, and the strain of host bone tissue was changed greatly, which was beneficial to the growth of bone tissue. The integrated fixation method is more stable, less stress and evenly distributed. Therefore, the integrated fixation device combined with the design of stiffness gradient can repair the large femoral bone defect well.
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