Evidence map›Paper›PMID 36803905›Full record

ArticleJournal of the International Neuropsychological Society : JINS2023

The association between cannabis use and subjective memory complaints in older adults in the United States.

Kyler Mulhauser, Benjamin M Hampstead, Lara N Coughlin, Mark A Ilgen

Open access · hybridAbstract read
In one paragraph

Article in Journal of the International Neuropsychological Society : JINS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Observational
  5. Marijuana use among community-dwelling older adults: A population-based study.International journal of geriatric psychiatry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kyler MulhauserDepartment of Psychiatry, University of Michigan, 2101 Commonwealth Blvd, Ann Arbor, MI, 48105, USA.ORCID 0000-0003-2755-0451
Benjamin M HampsteadDepartment of Psychiatry, University of Michigan, 2101 Commonwealth Blvd, Ann Arbor, MI, 48105, USA.
Lara N CoughlinDepartment of Psychiatry and Addiction Center, University of Michigan, 2800 Plymouth Rd., Bldg. 16, Ann Arbor, MI, 48109-2800, USA.
Mark A IlgenDepartment of Veterans Affairs, Center for Clinical Management Research (CCMR), Veterans Affairs Ann Arbor Healthcare System, 2800 Plymouth Rd., Bldg. 16, Ann Arbor, MI, 48109-2800, USA.
Michigan Medicine · USUniversity of Michigan · US

Funding

Research Program on Cognition and Neuromodulation Based Interventions (RP-CNBI)R35AG072262 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HAMPSTEAD, BENJAMIN MICHAEL · 2021 to 2025
$4.2M
Medical marijuana: Longitudinal trajectories in use, pain and functioningR01DA033397 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ILGEN, MARK A. · 2013 to 2016
$2.2M
Dual Diagnosis Inpatients: Telephone Monitoring RCT to Improve OutcomesI01HX000109 · VA · VETERANS ADMIN PALO ALTO HEALTH CARE SYS · PI ILGEN, MARK A., TIMKO, CHRISTINE D · 2011 to 2015
–
HSR&D Research Career Scientist AwardIK6HX002841 · VA · VETERANS HEALTH ADMINISTRATION · PI MARK A. ILGEN · 2020 to 2026
–
HSRD VA I01 HX000109HSRD VA IK6 HX002841NIA NIH HHS R35 AG072262NIDA NIH HHS R01 DA033397
6 · The paper itself

Abstract

objectiveThe U.S. population is aging and increasing numbers of older adults are using cannabis. Cognitive decline is common in older age and subjective memory complaints (SMC) have been associated with increased risk for dementia. While residual cognitive effects of cannabis use at younger ages are well understood, the links between cannabis use and cognition in older adults is less clear. The present study represents the first population-level analysis of cannabis use and SMC in older adults in the U.S.

methodWe used the National Survey of Drug Use and Health (NSDUH) dataset to evaluate SMC in respondents over age 50 (N = 26,399) according to past-year cannabis use.

resultsResults revealed that 13.2% (95%CI: 11.5%-15.0%) of those who reported cannabis use also reported SMC, compared to 6.4% (95%CI: 6.1%-6.8%) among individuals with no cannabis use. Logistic regression revealed a two-fold increase (OR = 2.21, 95%CI: 1.88-2.60) of reporting SMC in respondents who had used cannabis in the past year, which was attenuated (OR = 1.38, 95%CI: 1.10-1.72) when controlling for additional factors. Other covariates, including physical health conditions, misuse of other substances, and mental illness also significantly contributed to SMC outcomes.

conclusionsCannabis use represents a modifiable lifestyle factor that has potential for both risk and protective properties that may impact the trajectory of cognitive decline in older age. These hypothesis generating results are important for characterizing and contextualizing population-level trends related to cannabis use and SMC in older adults.

Indexed as

CannabisCognitive DysfunctionSubstance-Related DisordersAgedCognitionHealth SurveysHumansMiddle AgedUnited Statesagingcognitiondementiamarijuanarepresentative surveysubstance use

Identifiers

PMID36803905
PMCPMC10885780
OpenAlexW4321374544

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.