Evidence map›Paper›PMID 36803828›Full record

ArticleItalian journal of pediatrics2023

The bronchiolitis epidemic in 2021-2022 during the SARS-CoV-2 pandemic: experience of a third level centre in Northern Italy.

Martha Caterina Faraguna, Irene Lepri, Antonio Clavenna, Maurizio Bonati, Chiara Vimercati, Debora Sala, Alessandro Cattoni, Maria Luisa Melzi, Andrea Biondi

Open access · goldAbstract read
In one paragraph

Article in Italian journal of pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

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  12. Severe respiratory syncytial virus disease.Journal of intensive medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Martha Caterina FaragunaResidency in Pediatrics, University of Milano Bicocca, Monza, Italy. marthafaraguna@live.com.ORCID http://orcid.org/0000-0003-3426-2749
Irene LepriResidency in Pediatrics, University of Milano Bicocca, Monza, Italy. i.lepri@campus.unimib.it.
Antonio ClavennaLaboratory for Mother and Child Health, Department of Public Health, Istituto Di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Maurizio BonatiLaboratory for Mother and Child Health, Department of Public Health, Istituto Di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Chiara VimercatiDepartment of Pediatrics, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Debora SalaDepartment of Pediatrics, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Alessandro CattoniDepartment of Pediatrics, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Maria Luisa MelziDepartment of Pediatrics, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Andrea BiondiDepartment of Pediatrics, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Azienda Ospedaliera San Gerardo · ITMario Negri Institute for Pharmacological Research · ITUniversity of Milano-Bicocca · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study is to compare the 2021-2022 bronchiolitis season to the four previous years (2017-2018, 2018-2019, 2019-2020, 2020-2021) to see if there was an anticipation of the peak, an overall increase of cases, and an increased need of intensive care.

methodsA retrospective single-centre study in the San Gerardo Hospital Fondazione MBBM, Monza, Italy was performed. Emergency Departments (ED) visits of patients aged < 18 years and ≤ 12 months were analyzed: the incidence of bronchiolitis on total assessments, the urgency level at triage and the hospitalization rate were compared. Data of children admitted to the Pediatric Department due to bronchiolitis were analyzed in terms of need of intensive care, respiratory support (type and duration), length of hospital stay, main etiological agent, patient characteristics.

resultsDuring 2020-2021 (first pandemic period) an important reduction in the ED attendance for bronchiolitis was observed, while in 2021-2022 there was an increase in incidence of bronchiolitis (13% of visits in infants < 1 year) and in the rate of urgent accesses (p = 0.0002), but hospitalization rates did not differ compared to previous years. Furthermore, an anticipated peak in November 2021 was observed. In the 2021-2022 cohort of admitted children to the Pediatric Department, a statistically significative increased need of intensive care unit was detected (Odds Ratio 3.1, 95% CI 1.4-6.8 after adjustment for severity and clinical characteristics). Instead, respiratory support (type and duration) and length of hospital stay did not differ. RSV was the main etiological agent and RSV-bronchiolitis determined a more severe infection (type and duration of breathing support, intensive care need and length of hospital stay).

conclusionsDuring Sars-CoV-2 lockdowns (2020-2021), there was a dramatic decrease of bronchiolitis and others respiratory infections. In the following season, 2021-2022, an overall increase of cases with an anticipated peak was observed and data analysis confirmed that patients in 2021-2022 required more intensive care than children in the four previous seasons.

Indexed as

BronchiolitisCOVID-19Respiratory Syncytial Virus InfectionsChildCommunicable Disease ControlHospitalizationHumansInfantPandemicsRetrospective StudiesSARS-CoV-2BronchiolitisEpidemicRespiratory syncytial virusSars-CoV-2

Identifiers

PMID36803828
PMCPMC9942300
OpenAlexW4321366080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.