Evidence map›Paper›PMID 36803741›Full record

ArticleAmerican journal of respiratory and critical care medicine2023

Single-Cell Analysis Reveals Distinct Immune and Smooth Muscle Cell Populations that Contribute to Chronic Thromboembolic Pulmonary Hypertension.

Gayathri Viswanathan, Hélène Fradin Kirshner, Nour Nazo, Saba Ali, Asvin Ganapathi, Ian Cumming, Yonghua Zhuang, Issac Choi, Anmol Warman, Chanpreet Jassal and 5 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 75 citations in OpenAlex.

  1. Review
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  5. The transcriptional landscape of developing human trisomy 21 lungs.American journal of respiratory cell and molecular biology · 2026
    Article
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  12. Transcriptome Analysis IdentifiedJournal of the American Heart Association · 2025
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Gayathri ViswanathanDivision of Cardiology, Department of Medicine.ORCID 0000-0001-7395-919X
Hélène Fradin KirshnerDuke Center for Genomic and Computational Biology.ORCID 0000-0003-4110-0983
Nour NazoDivision of Cardiology, Department of Medicine.
Saba AliDivision of Cardiology, Department of Medicine.
Asvin GanapathiDivision of Cardiothoracic Surgery, Department of Surgery.ORCID 0000-0003-2765-3733
Ian CummingDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, and.
Yonghua ZhuangBiostatistics Shared Resource, University of Colorado Cancer Center.ORCID 0000-0002-1822-2395
Issac ChoiDivision of Cardiology, Department of Medicine.ORCID 0000-0001-7429-8418
Anmol WarmanDivision of Cardiology, Department of Medicine.ORCID 0000-0001-5564-6747
Chanpreet JassalDivision of Cardiology, Department of Medicine.
Susana Almeida-PetersDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, and.
John HaneyDivision of Cardiothoracic Surgery, Department of Surgery.
David CorcoranDuke Center for Genomic and Computational Biology.ORCID 0000-0001-7460-9247
Yen-Rei YuDivision of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado.ORCID 0000-0002-1984-7186
Sudarshan RajagopalDivision of Cardiology, Department of Medicine.ORCID 0000-0002-3443-5040
Center for Genomic Science · ITPulmonary and Allergy Associates · USDuke University · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Colorado Cancer Center · US

Funding

Role of Resident Monocytes in the Pathogenesis of Pulmonary Arterial HypertensionK08HL121185 · NHLBI · DUKE UNIVERSITY · PI YU, YEN-REI ANDREA · 2015 to 2019
$659k
Macrophage-specific Pair Immunoglobulin-like Type 2 Receptor beta (PILRB) regulation of Pulmonary HypertensionR03HL158640 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI YU, YEN-REI ANDREA · 2021 to 2022
$156k
NHLBI NIH HHS K08 HL121185NHLBI NIH HHS R03 HL158640
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hypertension, PulmonaryPulmonary EmbolismThrombosisCD8-Positive T-LymphocytesChronic DiseaseHumansInflammationMyocytes, Smooth MusclePulmonary ArteryReceptor, PAR-1Single-Cell AnalysisVascular RemodelingReceptor, PAR-1CTEPHmacrophagesprotease-activated receptor 1single-cell RNA sequencingsmooth muscle cells

Identifiers

PMID36803741
PMCPMC10595445
OpenAlexW4321435785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.