Evidence map›Paper›PMID 36803662›Full record

ArticleBMC cardiovascular disorders2023

Impact of health literacy and social support on medication adherence in patients with hypertension: a cross-sectional community-based study.

Aizhen Guo, Hua Jin, Jianbo Mao, Weihong Zhu, Ye Zhou, Xuhua Ge, Dehua Yu

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Article in BMC cardiovascular disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Impact of Interventions on Medication Adherence in Patients With Coexisting Diabetes and Hypertension.Health expectations : an international journal of public participation in health care and health policy · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aizhen GuoDepartment of General Practice, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, 200090, China.
Hua JinDepartment of General Practice, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, 200090, China.
Jianbo MaoChangbai Community Health Service Center, Yangpu District, Shanghai, 200093, China.
Weihong ZhuWujiaochang Community Health Service Center, Yangpu District, Shanghai, 200433, China.
Ye ZhouYanji Community Health Service Center, Yangpu District, Shanghai, 200093, China.
Xuhua GeDepartment of General Practice, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, 200090, China.
Dehua YuDepartment of General Practice, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, 200090, China. shgprc@yeah.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies have examined the associations of health literacy and social support with medication adherence among patients with hypertension. However, limited evidence exists regarding the mechanisms underlying the relationship between these factors and medication adherence. PURPOSE: To explore the prevalence of medication adherence and its determinants in patients with hypertension in Shanghai.

methodsA community-based cross-sectional study was conducted among 1697 participants with hypertension. We collected sociodemographic and clinical characteristics as well as data regarding health literacy, social support, and medication adherence using questionnaires. We examined interactions among the factors using a structural equation model.

resultsThe participants included 654 (38.54%) patients with a low degree of medication adherence and 1043 (61.46%) patients with a medium/high degree of adherence. Social support directly influenced adherence (β = 0.165, P < 0.001) and indirectly influenced adherence through health literacy (β = 0.087, P < 0.001). Health literacy directly influenced adherence (β = 0.291, P < 0.001). Education indirectly affected adherence through both social support (β = 0.048, P < 0.001) and health literacy (β = 0.080, P < 0.001). Moreover, there was a sequential mediating effect of social support and health literacy on the association between education and adherence (β = 0.025, P < 0.001). After controlling for age and marital status, similar results were also obtained, indicating a good model fit.

conclusionsThe degree of medication adherence among hypertensive patients needs to improve. Health literacy and social support had both direct and indirect effects on adherence, and thus, these factors should be considered as tools to improve adherence.

Indexed as

Health LiteracyHypertensionChinaCross-Sectional StudiesHumansMedication AdherenceSocial SupportSurveys and QuestionnairesEducational levelHealth literacyHypertensionMedication adherenceSocial supportStructural equation model

Identifiers

PMID36803662
PMCPMC9940429

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.