Evidence map›Paper›PMID 36803357›Full record

ArticleBMC infectious diseases2023

Incidence, susceptibility and outcomes of candidemia in adults living in Calgary, Alberta, Canada (2010-2018).

Samuel Bourassa-Blanchette, Marit M Biesheuvel, John C Lam, Alexander Kipp, Deirdre Church, Julie Carson, Bruce Dalton, Michael D Parkins, Herman W Barkema, Daniel B Gregson

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Epidemiology, Risk Factors and Clinical Outcome of Candidaemia:Sultan Qaboos University medical journal · 2025
    Observational
  5. Candidiasis epidemiology and outcomes including emergence ofAntimicrobial stewardship & healthcare epidemiology : ASHE · 2025
    Article
  6. Case reports in infectious diseases · 2025
    Article
  7. Review
  8. Article
  9. Candidemia Treatment is Improved by Infectious Disease Consultation: A Population-Based Cohort Study.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2024
    Article
  10. Invasive candidiasis.Nature reviews. Disease primers · 2024
    Review
  11. Article
  12. Candida albicans and Antifungal Peptides.Infectious diseases and therapy · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Samuel Bourassa-BlanchetteDepartment of Medicine Laboratory Medicine, Memorial University, St. John's, NL, Canada. Samuel.bourassablanc@ucalgary.ca.
Marit M BiesheuvelFaculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada.
John C LamDivision of Infectious Diseases, Department of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Alexander KippDepartment of Pathology and Laboratory Medicine, Division of Microbiology, University of Calgary, Calgary, AB, Canada.
Deirdre ChurchDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Julie CarsonDepartment of Pathology and Laboratory Medicine, Division of Microbiology, University of Calgary, Calgary, AB, Canada.
Bruce DaltonAlberta Health Services, Pharmacy Services, Calgary, AB, Canada.
Michael D ParkinsDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Herman W BarkemaFaculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada.
Daniel B GregsonDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Alberta Health Services · CAUniversity of Calgary · CACalgary Laboratory Services · CAMemorial University of Newfoundland · CAUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCandidemia is increasing in frequency and is associated with high mortality. We sought to determine the burden of illness, the population it affects and its resistance profile in our region.

methodsThe Calgary Zone (CZ) provides all care for residents of Calgary and surrounding communities (~ 1.69 million) via five tertiary hospitals each served by a common single laboratory for acute care microbiology. All adult patients in the CZ with at least one Candida spp.-positive blood culture between January 1, 2010, and December 31, 2018, were identified using microbiological data from Calgary Lab Services, the laboratory that processes > 95% of all blood culture samples in the CZ, were reviewed for the study.

resultsThe overall annual incidence of candidemia among individuals living in the CZ was 3.8 per 100,000 persons (Median age 61 years (IQR 48-72) and 221/455 (47.4%) were female). C. albicans was the most common species (50.6%), followed by C. glabrata, (24.0%). No other species accounted for more than 7% of cases. Overall mortality at 30, 90, and 365 days was 32.2, 40.1, and 48.1% respectively. Mortality rate did not differ by Candida species. Of individuals who developed candidemia, more than 50% died within the next year. No new resistance pattern has emerged in the most common Candida species in Calgary, Alberta.

conclusionsIn Calgary, Alberta, the incidence of candidemia has not increased in the last decade. C. albicans was the most common species and it remains susceptible to fluconazole.

Indexed as

CandidemiaAdultAlbertaAntifungal AgentsCandidaCandida albicansCandida glabrataFemaleFluconazoleHumansIncidenceMaleMicrobial Sensitivity TestsMiddle AgedAntifungal AgentsFluconazoleAntifungal susceptibilityCandidaFungemiaIncidenceMortality

Identifiers

PMID36803357
PMCPMC9940426
OpenAlexW4321372466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.