Evidence map›Paper›PMID 36803233›Full record

ArticleAutophagy2023

Atg1-dependent phosphorylation of Vps34 is required for dynamic regulation of the phagophore assembly site and autophagy in

Yongook Lee, Bongkeun Kim, Hae-Soo Jang, Won-Ki Huh

Open access · greenAbstract read
In one paragraph

Article in Autophagy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Multifunctional Roles of Autophagy in Fungi.Journal of fungi (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. mSphere · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Yeast Lsm Pro-Apoptotic Mutants Show Defects in Autophagy.International journal of molecular sciences · 2023
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yongook LeeSchool of Biological Sciences, Seoul National University, Seoul, Republic of Korea.
Bongkeun KimSchool of Biological Sciences, Seoul National University, Seoul, Republic of Korea.
Hae-Soo JangSchool of Biological Sciences, Seoul National University, Seoul, Republic of Korea.
Won-Ki HuhSchool of Biological Sciences, Seoul National University, Seoul, Republic of Korea.ORCID 0000-0002-9091-6594
Seoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macroautophagy/autophagy is a key catabolic pathway in which double-membrane autophagosomes sequester various substrates destined for degradation, enabling cells to maintain homeostasis and survive under stressful conditions. Several autophagy-related (Atg) proteins are recruited to the phagophore assembly site (PAS) and cooperatively function to generate autophagosomes. Vps34 is a class III phosphatidylinositol 3-kinase, and Atg14-containing Vps34 complex I plays essential roles in autophagosome formation. However, the regulatory mechanisms of yeast Vps34 complex I are still poorly understood. Here, we demonstrate that Atg1-dependent phosphorylation of Vps34 is required for robust autophagy activity in

Indexed as

Saccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAutophagosomesAutophagyAutophagy-Related ProteinsPhagosomesPhosphorylationAutophagy-Related ProteinsSaccharomyces cerevisiae ProteinsAtg1Atg18Atg8autophagynitrogen starvationSaccharomyces cerevisiaeVps34

Identifiers

PMID36803233
PMCPMC10392759
OpenAlexW4321371986

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.