Evidence map›Paper›PMID 36803115›Full record

ArticleDrug delivery2023

Polysialic acid-functionalized liposomes for efficient honokiol delivery to inhibit breast cancer growth and metastasis.

Xin Li, Shuang Guan, Henan Li, Dong Li, Dan Liu, Jing Wang, Wenquan Zhu, Guihua Xing, Liling Yue, Defu Cai and 1 more

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Xin LiInstitute of Medicine and Drug Research, Qiqihar Medical University, Qiqihar, P.R. China.
Shuang GuanInstitute of Medicine and Drug Research, Qiqihar Medical University, Qiqihar, P.R. China.
Henan LiInstitute of Medicine and Drug Research, Qiqihar Medical University, Qiqihar, P.R. China.
Dong LiInstitute of Medicine and Drug Research, Qiqihar Medical University, Qiqihar, P.R. China.
Dan LiuInstitute of Medicine and Drug Research, Qiqihar Medical University, Qiqihar, P.R. China.
Jing WangInstitute of Medicine and Drug Research, Qiqihar Medical University, Qiqihar, P.R. China.
Wenquan ZhuCollege of Pharmacy, Qiqihar Medical University, Qiqihar, P.R. China.
Guihua XingCollege of Pathology, Qiqihar Medical University, Qiqihar, P.R. China.
Liling YueInstitute of Medicine and Drug Research, Qiqihar Medical University, Qiqihar, P.R. China.
Defu CaiInstitute of Medicine and Drug Research, Qiqihar Medical University, Qiqihar, P.R. China.
Qi ZhangInstitute of Medicine and Drug Research, Qiqihar Medical University, Qiqihar, P.R. China.
Qiqihar Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To improve the anti-metastasis effects of honokiol (HNK) on breast cancer, we designed cationic liposomes (Lip) in which HNK was encapsulated into Lip, and its surface was modified with negatively charged polysialic acid (PSA-Lip-HNK) for efficient treatment of breast cancer. PSA-Lip-HNK possessed a homogeneous spherical shape and high encapsulation efficiency.

Indexed as

Breast NeoplasmsAllyl CompoundsAnimalsBiphenyl CompoundsCell Line, TumorHumansLignansLiposomesMicePhenolsSialic AcidsAllyl CompoundsBiphenyl CompoundshonokiolLignansliposomal honokiolLiposomesPhenolspolysialic acidSialic AcidsBreast cancerhonokiolliposomesmetastasispolysialic acid

Identifiers

PMID36803115
PMCPMC9946320
OpenAlexW4321453887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.