Evidence map›Paper›PMID 36803102›Full record

ArticleClinical pediatrics2023

A Comparison of Short Versus Long Course Intravenous Antibiotics When Treating Urinary Tract Infection in Infants <60 Days of Age.

Fadi Zu'bi, Martha Pokarowski, Rusul Al-Kutbi, Michelle Science, Janaki Vallipuram, Fardod O'Kelly, Michael Chua, Jeremy Friedman, Martin Koyle

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Fadi Zu'biDepartment of Urology, Rambam Health Care Campus, Haifa, Israel.
Martha PokarowskiDivision of Urology, The Hospital for Sick Children, Toronto, ON, Canada.ORCID 0000-0001-6647-7029
Rusul Al-KutbiDivision of Urology, The Hospital for Sick Children, Toronto, ON, Canada.
Michelle ScienceDivision of Infectious Diseases, The Hospital for Sick Children, Toronto, ON, Canada.
Janaki VallipuramDivision of Paediatric Medicine, The Hospital for Sick Children, Toronto, ON, Canada.
Fardod O'KellyDivision of Urology, Beacon Hospital, University College Dublin, Dublin, Ireland.
Michael ChuaDivision of Urology, The Hospital for Sick Children, Toronto, ON, Canada.
Jeremy FriedmanDivision of Infectious Diseases, The Hospital for Sick Children, Toronto, ON, Canada.
Martin KoyleDivision of Urology, The Hospital for Sick Children, Toronto, ON, Canada.
Hospital for Sick Children · CANazareth Hospital EMMS · ILUniversity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urinary tract infections (UTIs) are a common reason for hospitalization in infants younger than 60 days, and the optimal approach to intravenous (IV) antibiotic therapy upon UTI diagnosis in this cohort is unknown. We determined whether there was an association between IV antibiotic therapy duration (long [>3 days] vs short [≤3 days]) and treatment failure via a retrospective review of infants with confirmed UTIs receiving IV antibiotics at a tertiary referral center. A total of 403 infants were included; 39% were treated with ampicillin and cefotaxime, and 34% with ampicillin and gentamycin or tobramycin. The median IV antibiotic duration was 5 (interquartile range: 3-10) days, and 5% of patients experienced treatment failure. The treatment failure rate was similar in both short- and long-course IV antibiotic groups (

Indexed as

Anti-Bacterial AgentsUrinary Tract InfectionsAmpicillinGentamicinsHumansInfantRetrospective StudiesTreatment FailureAmpicillinAnti-Bacterial AgentsGentamicinsinfantsintravenous antibioticsreadmissionurinary tract infection

Identifiers

PMID36803102
PMCPMC10478320
OpenAlexW4321453076

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.