Evidence map›Paper›PMID 36802630›Full record

ArticleJournal of the American Chemical Society2023

Direct Proton-Coupled Electron Transfer between Interfacial Tyrosines in Ribonucleotide Reductase.

Jiayun Zhong, Clorice R Reinhardt, Sharon Hammes-Schiffer

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Low-barrier hydrogen bond powers long-range radical transfer in the metal-free ribonucleotide reductase.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Allosteric gating of radical transport in ribonucleotide reductase.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Conformationally gated multisite proton-coupled electron transfer in the ribonucleotide reductaseProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Mechanism of Lutein tobioRxiv : the preprint server for biology · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Tuning Energetics of 2 eChemistry (Weinheim an der Bergstrasse, Germany) · 2024
    Article
  13. Surface-Accelerated String Method for Locating Minimum Free Energy Paths.Journal of chemical theory and computation · 2024
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jiayun ZhongDepartment of Chemistry, Yale University, New Haven, Connecticut 06520, United States.
Clorice R ReinhardtDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520, United States.ORCID 0000-0002-6083-4950
Sharon Hammes-SchifferDepartment of Chemistry, Yale University, New Haven, Connecticut 06520, United States.ORCID 0000-0002-3782-6995
Yale University · US

Funding

Coupled Protons and Electrons in Biological SystemsR35GM139449 · NIGMS · YALE UNIVERSITY · PI HAMMES-SCHIFFER, SHARON · 2021 to 2025
$2.1M
NIGMS NIH HHS R35 GM139449
6 · The paper itself

Abstract

Ribonucleotide reductase (RNR) regulates DNA synthesis and repair in all organisms. The mechanism of

Indexed as

Ribonucleotide ReductasesTyrosineElectronsElectron TransportEscherichia coliModels, MolecularProtonsWaterProtonsRibonucleotide ReductasesTyrosineWater

Identifiers

PMID36802630
PMCPMC10344599
OpenAlexW4321368242

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.