Evidence map›Paper›PMID 36802558›Full record

ArticleInorganic chemistry2023

Dual Role of Glutathione as a Reducing Agent and Cu-Ligand Governs the ROS Production by Anticancer Cu-Thiosemicarbazone Complexes.

Alessandra G Ritacca, Enrico Falcone, Iman Doumi, Bertrand Vileno, Peter Faller, Emilia Sicilia

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Inorganic chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

  1. Transmetalation in Cancer Pharmacology.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Alessandra G RitaccaDepartment of Chemistry and Chemical Technologies, Università della Calabria, Ponte P. Bucci, 87036 Arcavacata di Rende (CS), Italy.
Enrico FalconeInstitut de Chimie (UMR 7177), University of Strasbourg - CNRS, 4 Rue Blaise Pascal, 67000 Strasbourg, France.ORCID 0000-0002-1944-3552
Iman DoumiInstitut de Chimie (UMR 7177), University of Strasbourg - CNRS, 4 Rue Blaise Pascal, 67000 Strasbourg, France.
Bertrand VilenoInstitut de Chimie (UMR 7177), University of Strasbourg - CNRS, 4 Rue Blaise Pascal, 67000 Strasbourg, France.
Peter FallerInstitut de Chimie (UMR 7177), University of Strasbourg - CNRS, 4 Rue Blaise Pascal, 67000 Strasbourg, France.ORCID 0000-0001-8013-0806
Emilia SiciliaDepartment of Chemistry and Chemical Technologies, Università della Calabria, Ponte P. Bucci, 87036 Arcavacata di Rende (CS), Italy.ORCID 0000-0001-5952-9927
Centre National de la Recherche Scientifique · FRUniversity of Calabria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

α-Pyridyl thiosemicarbazones (TSC) such as Triapine (3AP) and Dp44mT are a promising class of anticancer agents. Contrary to Triapine, Dp44mT showed a pronounced synergism with Cu

Indexed as

Antineoplastic AgentsThiosemicarbazonesCell Line, TumorCopperGlutathioneLigandsPyridinesReactive Oxygen SpeciesReducing Agents3-aminopyridine-2-carboxaldehyde thiosemicarbazoneAntineoplastic AgentsCopperdi-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazoneGlutathioneLigandsPyridinesReactive Oxygen SpeciesReducing AgentsThiosemicarbazones

Identifiers

PMID36802558
PMCPMC9996813
OpenAlexW4321365780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.