ArticleProceedings of the National Academy of Sciences of the United States of America2023
A synthetic porphyrin as an effective dual antidote against carbon monoxide and cyanide poisoning.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Conjugates of Heme and Intrinsically Disordered Peptides toward the Development of Synthetic Artificial Oxygen Carriers.Bioconjugate chemistry · 2026Article
- Cationic Permethylated Cyclodextrins Capable of Self-Assembling Into Linear Nanostructures in Water.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- Immobilized neuroglobin scavenges carbon monoxide from circulating carboxyhemoglobin.bioRxiv : the preprint server for biology · 2026Article
- When Red Blood Cells Meet Carbon Monoxide: Yin and Yang in Medicines and Pharmaceuticals.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Protic small molecule bioregulators.Redox biology · 2025Review
- CORM-A1 delivers carbon monoxide to the kidney and alleviates post-ischemic renal dysfunction in rat and swine models.Physiological reports · 2025Article
- Quantification of carbon monoxide (CO) in postmortem human brain tissues after CO poisoning.Scientific reports · 2025Article
- CO Complexation by Ru(II) and Os(II) Porphyrin Complexes Sheds Light on the Relative Importance of Thermodynamic Stability and Kinetic Lability for CO Poisoning Antidotes.Organometallics · 2025Article
- Detoxification of hydrogen sulfide by synthetic heme model compounds.Scientific reports · 2024Article
- Carbon Monoxide as a Potential Therapeutic Agent: A Molecular Analysis of Its Safety Profiles.Journal of medicinal chemistry · 2024Review
- Carbon Monoxide Poisoning: From Microbes to Therapeutics.Annual review of medicine · 2024Review
- Artificial porphyrin molecules clean up carbon monoxide and cyanide.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 6 institutions in 2 countries.
Funding
Abstract
Simultaneous poisoning by carbon monoxide (CO) and hydrogen cyanide is the major cause of mortality in fire gas accidents. Here, we report on the invention of an injectable antidote against CO and cyanide (CN
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.