Evidence map›Paper›PMID 36802336›Full record

Trial reportAmerican journal of respiratory and critical care medicine2023

Effectiveness of Bedaquiline Use beyond Six Months in Patients with Multidrug-Resistant Tuberculosis.

Letizia Trevisi, Miguel A Hernán, Carole D Mitnick, Uzma Khan, Kwonjune J Seung, Michael L Rich, Mathieu Bastard, Helena Huerga, Nara Melikyan, Sidney A Atwood and 18 more

Abstract readClinical Trial
In one paragraph

Trial report in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Pregnancy and Birth Outcomes in Patients With Multidrug-Resistant Tuberculosis Treated With Regimens That Include New and Repurposed Drugs.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  13. Article
  14. "Weighting" the Evidence: How Much Bedaquiline Is Enough?American journal of respiratory and critical care medicine · 2023
    Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

28 authors.

Letizia TrevisiDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts.
Miguel A HernánCAUSALab, Departments of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.
Carole D MitnickDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts.
Uzma KhanInteractive Research and Development Global, Singapore, Singapore.
Kwonjune J SeungDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts.
Michael L RichDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts.
Mathieu BastardField Epidemiology Department, Epicentre, Paris, France.
Helena HuergaField Epidemiology Department, Epicentre, Paris, France.
Nara MelikyanField Epidemiology Department, Epicentre, Paris, France.
Sidney A AtwoodDivision of Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts.
Zaza AvalianiNational Center for Tuberculosis and Lung Diseases, Tbilisi, Georgia.
Felix LlanosUnidad de Tuberculosis, Hospital Nacional Dos de Mayo, Lima, Peru.
Mohammad Manzur-Ul-AlamInteractive Research and Development, Dhaka, Bangladesh.
Khin ZarliMédecins sans Frontières, Yangon, Myanmar.
Amsalu Bekele BinegdieDepartment of Internal Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Sana AdnanIndus Hospital and Health Network, Karachi, Pakistan.
Arusyak MelikyanMédecins sans Frontières, Yerevan, Armenia.
Alain GelinZanmi Lasante, Port-au-Prince, Haiti.
Afshan K IsaniNational Core Research Group, Stop TB Partnership, Islamabad, Pakistan.
Dmitry VetushkoRepublican Scientific and Practical Centre of Pulmonology and Tuberculosis, Minsk, Belarus.
Zhenisgul DaugarinaAstana City Center of Phthisiopulmonology, Astana, Kazakhstan.
Patrick NkundanyirazoPartners in Health, Maseru, Lesotho.
Fauziah Asnely PutriInteractive Research and Development Global, Singapore, Singapore.
Charles VilbrunGHESKIO, Port-au-Prince, Haiti.
Munira KhanInteractive Research and Development, Durban, South Africa.
Catherine HewisonMedical Department, Médecins sans Frontières, Paris, France; and.
Palwasha Y KhanDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Molly F FrankeDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-4890-5728

Funding

Strengthening evidence on optimal multidrug-resistant tuberculosis treatment regimens through improved epidemiologic methodsR01AI146095 · NIAID · HARVARD MEDICAL SCHOOL · PI FRANKE, MOLLY FORREST · 2020 to 2024
$3.6M
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antitubercular AgentsTuberculosis, Multidrug-ResistantClofazimineDiarylquinolinesHumansAntitubercular AgentsbedaquilineClofazimineDiarylquinolinesdurationendTB observational studyinverse probability weightingrifampicin-resistant TBtarget trial

Identifiers

PMID36802336
PMCPMC10263131

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.