Evidence map›Paper›PMID 36802330›Full record

ArticleJournal of medicinal chemistry2023

Multitarget-Directed Gallium(III) Tris(acyl-pyrazolonate) Complexes Induce Ferroptosis in Cancer Cells via Dysregulation of Cell Redox Homeostasis and Inhibition of the Mevalonate Pathway.

Daphne Romani, Fabio Marchetti, Corrado Di Nicola, Massimiliano Cuccioloni, Chunmei Gong, Anna Maria Eleuteri, Agustín Galindo, Farzaneh Fadaei-Tirani, Massimo Nabissi, Riccardo Pettinari

Open access · hybridFull text read
In one paragraph

Article in Journal of medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
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  7. AChemical science · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Daphne Romani
Corrado Di NicolaORCID 0000-0002-0958-6103
Massimiliano CuccioloniORCID 0000-0002-6025-1990
Chunmei Gong
Anna Maria Eleuteri
Agustín GalindoDepartamento de Química Inorgánica, Facultad de Química, Universidad de Sevilla, Aptdo 1203, 41071 Sevilla, Spain.ORCID 0000-0002-2772-9171
Farzaneh Fadaei-TiraniInstitut of Chemical Sciences and Engineering, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne CH-1015, Switzerland.ORCID 0000-0002-7515-7593
Massimo Nabissi
Riccardo PettinariORCID 0000-0002-6313-4431
Università di Camerino · ITÉcole Polytechnique Fédérale de Lausanne · CHUniversidad de Sevilla · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of Ga(Q

Indexed as

Antineoplastic AgentsCoordination ComplexesFerroptosisGalliumNeoplasmsApoptosisCell Line, TumorHomeostasisHumansMevalonic AcidOxidation-ReductionReactive Oxygen SpeciesAntineoplastic AgentsCoordination ComplexesGalliumMevalonic AcidReactive Oxygen Species

Identifiers

PMID36802330
PMCPMC10009752
OpenAlexW4321435653

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read124
table measurements read31
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.