Evidence map›Paper›PMID 36802301›Full record

ArticleJournal of materials science. Materials in medicine2023

A novel antibacterial and fluorescent coating composed of polydopamine and carbon dots on the surface of orthodontic brackets.

Yixi Wang, Chuanyang Ding, Zhangjie Ge, Zhipeng Li, Lixin Chen, Xiaolong Guo, Genxi Dong, Ping Zhou

Abstract read
In one paragraph

Article in Journal of materials science. Materials in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yixi Wang *School and Hospital of Stomatology, Lanzhou University, No.222 Tianshui South Road, Chengguan District, Lanzhou, 730000, China.
Chuanyang Ding *School and Hospital of Stomatology, Lanzhou University, No.222 Tianshui South Road, Chengguan District, Lanzhou, 730000, China.
Zhangjie Ge *School and Hospital of Stomatology, Lanzhou University, No.222 Tianshui South Road, Chengguan District, Lanzhou, 730000, China.
Zhipeng LiSchool and Hospital of Stomatology, Lanzhou University, No.222 Tianshui South Road, Chengguan District, Lanzhou, 730000, China.
Lixin ChenSchool and Hospital of Stomatology, Lanzhou University, No.222 Tianshui South Road, Chengguan District, Lanzhou, 730000, China.
Xiaolong GuoSchool and Hospital of Stomatology, Lanzhou University, No.222 Tianshui South Road, Chengguan District, Lanzhou, 730000, China.
Genxi DongSchool and Hospital of Stomatology, Lanzhou University, No.222 Tianshui South Road, Chengguan District, Lanzhou, 730000, China. gxdong@lzu.edu.cn.
Ping ZhouSchool and Hospital of Stomatology, Lanzhou University, No.222 Tianshui South Road, Chengguan District, Lanzhou, 730000, China. zhoup@lzu.edu.cn.ORCID http://orcid.org/0000-0002-6128-3951

Funding

Fundamental Research Funds for Central Universities of the Central South University lzujbkj-2019-ct07, lzujbky-2021-ey14 and lzujbky-2021-kb05Gansu Provincial Natural Science Foundation 20JR5RA253
6 · The paper itself

Abstract

Many kinds of antibacterial coatings have been designed to prevent the adherence of bacteria onto the surface of a fixed orthodontic device of brackets. However, the problems such as weak binding force, undetectable, drug resistance, cytotoxicity and short duration needed to be solved. Thus, it has great value in developing novel coating methods with long-term antibacterial and fluorescence properties according to the clinical application of brackets. In this study, we synthesized blue fluorescent carbon dots (HCDs) using the traditional Chinese medicinal honokiol, which could cause irreversible killing effects on both gram-positive and gram-negative bacteria through positive charges on the surface and inducing reactive oxygen species (ROS) production. Based on this, the surface of brackets was serially modified with polydopamine and HCDs, taking advantage of the strong adhesive properties as well as the negative surface charge of polydopamine particles. It is found that this coating exhibits stable antibacterial properties in 14 days with good biocompatibility, which can provide a new solution and strategy to solve the series of hazards caused by bacterial adhesion on the surface of orthodontic brackets.

Indexed as

Gram-Negative BacteriaOrthodontic BracketsAnti-Bacterial AgentsCarbonColoring AgentsGram-Positive BacteriaIndolesPolymersSurface PropertiesAnti-Bacterial AgentsCarbonColoring AgentsIndolespolydopaminePolymersAntibacterial coatingBracketsHonokiol carbon dotsPolydopamineReactive oxygen species

Identifiers

PMID36802301
PMCPMC9943946

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.