Evidence map›Paper›PMID 36802243›Full record

ArticleJournal of chemical information and modeling2023

Mechanistic Basis for a Connection between the Catalytic Step and Slow Opening Dynamics of Adenylate Kinase.

Beata Dulko-Smith, Pedro Ojeda-May, Jörgen Ådén, Magnus Wolf-Watz, Kwangho Nam

Abstract read
In one paragraph

Article in Journal of chemical information and modeling, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Allosteric communication between ligand binding domains modulates substrate inhibition in adenylate kinase.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Beata Dulko-SmithDepartment of Chemistry and Biochemistry, University of Texas at Arlington, Arlington, Texas 76019, United States.
Pedro Ojeda-MayHigh Performance Computing Centre North (HPC2N), Umeå University, Umeå SE-90187, Sweden.
Jörgen ÅdénDepartment of Chemistry, Umeå University, Umeå SE-90187, Sweden.ORCID 0000-0002-4480-1219
Magnus Wolf-WatzDepartment of Chemistry, Umeå University, Umeå SE-90187, Sweden.ORCID 0000-0002-9098-7974
Kwangho NamDepartment of Chemistry and Biochemistry, University of Texas at Arlington, Arlington, Texas 76019, United States.ORCID 0000-0003-0723-7839

Funding

Multiscale Modeling of Protein Kinase Structure, Catalysis and AllosteryR01GM132481 · NIGMS · UNIVERSITY OF TEXAS ARLINGTON · PI Kwangho Nam · 2019 to 2026
$1.7M
NIGMS NIH HHS R01 GM132481
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adenylate KinaseMolecular Dynamics SimulationCatalysisCatalytic DomainEscherichia coliProtein ConformationAdenylate Kinase

Identifiers

PMID36802243
PMCPMC11779523

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.