Evidence map›Paper›PMID 36802222›Full record

ArticleApplied and environmental microbiology2023

Novel Insights into the Molecular Mechanisms Underlying Robustness and Stability in Probiotic Bifidobacteria.

Marie Schöpping, Anisha Goel, Kristian Jensen, Ricardo Almeida Faria, Carl Johan Franzén, Ahmad A Zeidan

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Proteomic Analysis ofFoods (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marie SchöppingSystems Biology, R&D Discovery, Chr. Hansen A/S, Hørsholm, Denmark.ORCID 0000-0003-0929-7552
Anisha GoelProcess Upscaling, Chr. Hansen A/S, Hørsholm, Denmark.
Kristian JensenSystems Biology, R&D Discovery, Chr. Hansen A/S, Hørsholm, Denmark.ORCID 0000-0002-2796-805X
Ricardo Almeida FariaBiochemical Assays, Chr. Hansen A/S, Hørsholm, Denmark.
Carl Johan FranzénDivision of Industrial Biotechnology, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.ORCID 0000-0001-7540-2002
Ahmad A ZeidanSystems Biology, R&D Discovery, Chr. Hansen A/S, Hørsholm, Denmark.ORCID 0000-0001-9984-5625

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some probiotic bifidobacteria are highly robust and shelf-stable, whereas others are difficult to produce, due to their sensitivity to stressors. This limits their potential use as probiotics. Here, we investigate the molecular mechanisms underlying the variability in stress physiologies of Bifidobacterium animalis subsp.

Indexed as

Bifidobacterium animalisProbioticsBifidobacteriumGene Expression ProfilingIntestinesamino acids utilization and synthesisBifidobacteria longum subsp. longumBifidobacterium animalis subsp. lactiscell membrane fatty acid profilecell surface hydrophobicitymetabolite productionprobiotic bacteriarobustnessstabilitytranscriptomic

Identifiers

PMID36802222
PMCPMC10057886

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.