ArticleEuropean journal of applied physiology2023
The benefits of regular aerobic exercise training on cerebrovascular function and cognition in older adults.
Article in European journal of applied physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Moving Beyond Outcome-Based Exercise Studies in Cognitive Aging: A Mechanism-Informed Narrative Review of Cerebrovascular Anchors and Supportive Biological Endpoints.Life (Basel, Switzerland) · 2026Review
- Cerebral Blood and Cerebrospinal Fluid Flow Dynamics in Endurance Athletes: Associations With Aortic Recoil and Heart Rate.Scandinavian journal of medicine & science in sports · 2026Article
- Cardiorespiratory fitness in relation to cerebral vascular and metabolic health in older adults with coronary artery disease.GeroScience · 2026Article
- Comparative effects of Baduanjin and square dance on working memory, executive function performance, mood, and fatigue in older women: a randomized controlled trial.Frontiers in psychology · 2026Article
- Aerobic exercise versus acupuncture as adjuncts to acetylcholinesterase inhibitors in Alzheimer's disease: a systematic review and Bayesian network meta-analysis.American journal of clinical and experimental immunology · 2026Review
- Neurophysiological mechanisms underlying cardiovascular adaptations to exercise: A narrative review.Physiological reports · 2025Review
- Exploring Strategies to Promote Exercise as a Viable Obesity and Chronic Disease Treatment.Nutrients · 2025Review
- Effects of eccentric resistance training after stroke on body function, activities of daily living and cognitive function: A review.Sports medicine and health science · 2025Review
- Lifestyle interventions for dementia risk reduction: A review on the role of physical activity and diet in Western and Asian Countries.The journal of prevention of Alzheimer's disease · 2025Review
- Enhancing active aging through exercise: a comparative study of high-intensity interval training and continuous aerobic training benefits.Frontiers in aging · 2025Review
- Enhancing motivation for initiation and continuation of physical activity in older adults using sensory augmentation devices: a preliminary pre-post study.Frontiers in sports and active living · 2025Article
- Exercise as a Therapeutic Strategy to Improve Cerebrovascular Function and Cognition in Breast Cancer Survivors: A Scoping Review.Journal of clinical medicine · 2024Article
- Neuropsychology and Vascular Cognitive Impairment and Dementia.Neurologic clinics · 2024Review
- Arterial Aging and Cerebrovascular Function: Impact of Aerobic Exercise Training in Older Adults.Aging and disease · 2024Review
- The Role of a Ketogenic Diet in the Treatment of Dementia in Type 2 Diabetes Mellitus.Nutrients · 2023Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We compared the differences in cerebrovascular and cognitive function between 13 aerobic exercise trained, older adults and 13 age-, height- and sex-matched sedentary, untrained controls. We determined whether other measures accounted for differences in cerebrovascular and cognitive function between these groups and examined the associations between these functions. Participants undertook anthropometric, mood, cardiovascular, exercise performance, strength, cerebrovascular, and cognitive measurements, and a blood collection. Transcranial Doppler ultrasonography determined cerebrovascular responsiveness (CVR) to hypercapnia and cognitive stimuli. The trained group had a higher CVR to hypercapnia (80.3 ± 7.2 vs 35.1 ± 6.7%, P < 0.001), CVR to cognitive stimuli (30.1 ± 2.9 vs 17.8 ± 1.4%, P = 0.001) and total composite cognitive score (117 ± 2 vs 98 ± 4, P < 0.001) than the controls. These parameters no longer remained statistically different between the groups following adjustments for covariates. There were positive correlations between the total composite cognitive score and CVR to hypercapnia (r = 0.474, P = 0.014) and CVR to cognitive stimuli (r = 0.685, P < 0.001). We observed a relationship between cerebrovascular and cognitive function in older adults and an interaction between regular lifelong aerobic exercise training and cardiometabolic factors that may directly influence these functions.
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