Observational studyJournal of perinatology : official journal of the California Perinatal Association2023
Association of full premedication on tracheal intubation outcomes in the neonatal intensive care unit: an observational cohort study.
Observational study in Journal of perinatology : official journal of the California Perinatal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 10 citations in OpenAlex.
- Reducing tracheal intubation adverse events and severe desaturations by increasing intubation premedication use in infants <1500 g: a quality improvement initiative.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Improving LISA Practice: An Ongoing Observational Quality Improvement Initiative Following Initiation of Less-Invasive Surfactant Administration in a Level IV NICU.Children (Basel, Switzerland) · 2026Article
- Success and safety of neonatal endotracheal tube exchanges: a NEAR4NEOS multicentre retrospective cohort study.Archives of disease in childhood. Fetal and neonatal edition · 2025Observational
- Complete atrioventricular block during neonatal intubation: a case report.Resuscitation plus · 2025Article
- Continuous improvement of non-emergent neonatal intubations in a level IV NICU.Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- Neonatal Airway Management.Children (Basel, Switzerland) · 2024Article
- Success rates and adverse events during neonatal intubation: Lessons learned from an international registry.Seminars in fetal & neonatal medicine · 2023Review
- Increasing Premedication for Neonatal Intubation: A Quality Improvement Initiative.Pediatric quality & safetyArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveEvaluate the association of short-term tracheal intubation (TI) outcomes with premedication in the NICU. STUDY
designObservational single-center cohort study comparing TIs with full premedication (opiate analgesia and vagolytic and paralytic), partial premedication, and no premedication. The primary outcome is adverse TI associated events (TIAEs) in intubations with full premedication compared to those with partial or no premedication. Secondary outcomes included change in heart rate and first attempt TI success.
results352 encounters in 253 infants (median gestation 28 weeks, birth weight 1100 g) were analyzed. TI with full premedication was associated with fewer TIAEs aOR 0.26 (95%CI 0.1-0.6) compared with no premedication, and higher first attempt success aOR 2.7 (95%CI 1.3-4.5) compared with partial premedication after adjusting for patient and provider characteristics.
conclusionThe use of full premedication for neonatal TI, including an opiate, vagolytic, and paralytic, is associated with fewer adverse events compared with no and partial premedication.
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