Evidence map›Paper›PMID 36801170›Full record

ArticleClinical genitourinary cancer2023

Practice Patterns Regarding Female Reproductive Organ-Sparing and Nerve-Sparing Radical Cystectomy Among Urologic Oncologists in the United States.

Natasha Gupta, Lauren Kucirka, Alice Semerjian, Phillip M Pierorazio, Stacy Loeb, Trinity J Bivalacqua

Open access · greenAbstract read
In one paragraph

Article in Clinical genitourinary cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Natasha GuptaDepartment of Urology and Population Health, New York University and Manhattan Veterans Affairs, New York City, NY. Electronic address: natasha.gupta@nyulangone.org.
Lauren KucirkaDivision of Maternal Fetal Medicine, Department of Gynecology and Obstetrics, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Alice SemerjianTrinity Health IHA, Ann Arbor, MI.
Phillip M PierorazioDepartment of Urology, University of Pennsylvania, Philadelphia, PA.
Stacy LoebDepartment of Urology and Population Health, New York University and Manhattan Veterans Affairs, New York City, NY.
Trinity J BivalacquaDepartment of Urology, University of Pennsylvania, Philadelphia, PA.
University of Pennsylvania · USNew York University · USTrinity Health · USUniversity of North Carolina at Chapel Hill · USVeterans Health Administration · US

Funding

Project-005UL1TR001445 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BREDELLA, MIRIAM ANTOINETTE, HOCHMAN, JUDITH S · 2015 to 2025
$103.5M
NYU Training Program in Healthcare Delivery Science and Population Health ResearchT32HS026120 · AHRQ · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HORWITZ, LEORA, SCHWARTZ, MARK D · 2018 to 2023
$3.4M
AHRQ HHS T32 HS026120NCATS NIH HHS UL1 TR001445
6 · The paper itself

Abstract

backgroundFemale reproductive organ-sparing (ROS) and nerve-sparing radical cystectomy (RC) techniques have been shown to be oncologically safe and to improve sexual function outcomes among select patients with organ-confined disease. We sought to characterize practice patterns regarding female ROS and nerve-sparing RC among US urologists. PATIENTS AND

methodsWe conducted a cross-sectional survey of members of the Society of Urologic Oncology to assess provider-reported frequency of ROS and nerve-sparing RC in premenopausal and postmenopausal patients with non-muscle-invasive bladder cancer that failed intravesical therapy or clinically localized muscle-invasive bladder cancer.

resultsAmong 101 urologists, 80 (79.2%) reported that they routinely resect the uterus/cervix, 68 (67.3%) the neurovascular bundle, 49 (48.5%) the ovaries, and 19 (18.8%) a portion of the vagina when performing RC in premenopausal patients with organ-confined disease. When asked about changes to approach in postmenopausal patients, 71 participants (70.3%) reported that they were less likely to spare the uterus/cervix, 44 (43.6%) were less likely to spare the neurovascular bundle, 70 (69.3%) were less likely to spare the ovaries, and 23 (22.8%) were less likely to spare a portion of the vagina.

conclusionWe identified significant gaps in adoption of female ROS and nerve-sparing RC techniques for patients with organ-confined disease, despite evidence that ROS and nerve-sparing techniques are oncologically safe and can optimize functional outcomes in select patients. Future efforts should improve provider training in and education about ROS and nerve-sparing RC to improve postoperative outcomes among female patients.

Indexed as

CystectomyUrinary Bladder NeoplasmsCross-Sectional StudiesFemaleHumansOrgan Sparing TreatmentsReactive Oxygen SpeciesUnited StatesUrinary BladderReactive Oxygen SpeciesBladder cancerFemale sexual functionOperative technique

Identifiers

PMID36801170
PMCPMC12497475
OpenAlexW4318159344

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.