ArticleThe journal of headache and pain2023
Spatio-temporal dynamics of resting-state brain networks are associated with migraine disability.
Article in The journal of headache and pain, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Network localization of regional intrinsic neural activity alterations in migraine and their neurochemical correlates.Frontiers in neurology · 2026Pooled it
- Resting-state electroencephalography and magnetoencephalography in migraine-a systematic review and meta-analysis.The journal of headache and pain · 2024Pooled it
- EEG microstates and dynamic functional connectivity reveal stage-specific brain networks in subjective tinnitus.iScience · 2026Article
- Effects of Social Media Use on Brain Dynamics in Young Male Adults: Multistage Concurrent Electroencephalography-Functional Magnetic Resonance Imaging Study.JMIR medical informatics · 2026Article
- EEG Connectivity Signatures in Migraine and Tension-Type Headache: A Multimethod ROI-Based Functional Connectivity and Machine-Learning Analysis.Journal of clinical medicine · 2026Article
- Multiplatform Morphometric Profiling of Whole-Brain, Cerebellar Subregional, and Thalamic Nuclei Alterations in Pediatric Migraine Without Aura.Diagnostics (Basel, Switzerland) · 2026Article
- Integrated anatomical and functional connectivity mapping in episodic migraine: a spectral graph theory approach.Scientific reports · 2026Article
- Topological signatures differentiating episodic and chronic phenotypes in migraine without aura: a multi-scale analysis revealing divergent network profiles.The journal of headache and pain · 2026Article
- Fusion of Multi-Paradigm EEG Microstate Features to Enhance the Recognition of Mild Cognitive Impairment.Brain and behavior · 2026Article
- State-specific disruptions of dynamic functional connectivity in young migraine without aura: a hidden Markov model approach.Frontiers in neuroscience · 2026Article
- Reduced brain entropy in migraine with partial restoration during attacks: A resting-state fMRI study.medRxiv : the preprint server for health sciences · 2025Article
- Differential resting-state MEG microstate patterns in migraineurs: a cross-sectional study.The journal of headache and pain · 2025Article
- Neural oscillation mechanisms of repetitive subconcussive impacts: a network study of microstate-specific cross-frequency coupling.The journal of headache and pain · 2025Article
- Analysis of brain dynamics changes in patients with cerebral small vessel disease-related cognitive impairment based on electroencephalogram microstates.European journal of medical research · 2025Article
- Study on Large-Scale Brain Network Abnormalities in Patients With Beta-Thalassemia.Brain and behavior · 2025Article
- Electroencephalographic Biomarkers for Neuropsychiatric Diseases: The State of the Art.Bioengineering (Basel, Switzerland) · 2025Review
- Electroencephalographic Resting-State Microstates are Unstable in Visual Snow Syndrome.Brain and behavior · 2025Article
- Eeg Microstates and Balance Parameters for Stroke Discrimination: A Machine Learning Approach.Brain topography · 2025Article
- Abnormal alterations in structure-function coupling at the modular level in patients with postherpetic neuralgia.Scientific reports · 2025Article
- Brain temporal dynamics correlate with clinical traits, spontaneous arm movements, and recovery in middle cerebral artery stroke.Frontiers in human neuroscience · 2025Article
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Authors and funding
8 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveThe changes in resting-state functional networks and their correlations with clinical traits remain to be clarified in migraine. Here we aim to investigate the brain spatio-temporal dynamics of resting-state networks and their possible correlations with the clinical traits in migraine.
methodsTwenty Four migraine patients without aura and 26 healthy controls (HC) were enrolled. Each included subject underwent a resting-state EEG and echo planar imaging examination. The disability of migraine patients was evaluated by Migraine Disability Assessment (MIDAS). After data acquisition, EEG microstates (Ms) combining functional connectivity (FC) analysis based on Schafer 400-seven network atlas were performed. Then, the correlation between obtained parameters and clinical traits was investigated.
resultsCompared with HC group, the brain temporal dynamics depicted by microstates showed significantly increased activity in functional networks involving MsB and decreased activity in functional networks involving MsD; The spatial dynamics were featured by decreased intra-network FC within the executive control network( ECN) and inter-network FC between dorsal attention network (DAN) and ECN (P < 0.05); Moreover, correlation analysis showed that the MIDAS score was positively correlated with the coverage and duration of MsC, and negatively correlated with the occurrence of MsA; The FC within default mode network (DMN), and the inter-FC of ECN- visual network (VN), ECN- limbic network, VN-limbic network was negatively correlated with MIDAS. However, the FC of DMN-ECN was positively correlated with MIDAS; Furthermore, significant interactions between the temporal and spatial dynamics were also obtained.
conclusionsOur study confirmed the notion that altered spatio-temporal dynamics exist in migraine patients during resting-state. And the temporal dynamics, the spatial changes and the clinical traits such as migraine disability interact with each other. The spatio-temporal dynamics obtained from EEG microstate and fMRI FC analyses may be potential biomarkers for migraine and with a huge potential to change future clinical practice in migraine.
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