Evidence map›Paper›PMID 36800233›Full record

ArticleAging2023

Circ_0001052 promotes cardiac hypertrophy via elevating Hipk3.

Mengyue Yang, Weichen Wang, Longlong Wang, Yuze Li

Open access · hybridFull text read
In one paragraph

Article in Aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  10. Article
  11. CircRNA-mediated regulation of cardiovascular disease.Frontiers in cardiovascular medicine · 2024
    Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mengyue YangDepartment of Cardiology, The First Hospital of China Medical University, Shenyang, Liaoning 110001, China.
Weichen WangDepartment of Cardiology, The First Hospital of China Medical University, Shenyang, Liaoning 110001, China.
Longlong WangDepartment of Cardiology, The First Hospital of China Medical University, Shenyang, Liaoning 110001, China.
Yuze LiDepartment of Cardiology, The First Hospital of China Medical University, Shenyang, Liaoning 110001, China.
China Medical University · CNFirst Hospital of China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac hypertrophy (CH) is a crucial risk factor for sudden death. Circular RNAs (circRNAs) exert significant effects in various biological and pathological processes. Circ_0001052 is sourced from Hipk3 (homeodomain-interacting protein kinase 3) and is reported to aggravate myocardial fibrosis. The purpose of the current study was to clarify the role and mechanism of circ-Hipk3 in CH. Transverse aortic constriction (TAC) was used to create an

Indexed as

Aortic Valve StenosisMicroRNAsPeptide HormonesRNA, CircularAngiotensin IIBiological AssayCardiomegalyCell ProliferationHumansIntracellular Signaling Peptides and ProteinsProtein Serine-Threonine KinasesSerine-Arginine Splicing FactorsAngiotensin IIHIPK3 protein, humanIntracellular Signaling Peptides and ProteinsMicroRNAsPeptide HormonesProtein Serine-Threonine KinasesRNA, CircularSerine-Arginine Splicing FactorsSRSF1 protein, humancardiac hypertrophycircRNAHipk3Srsf1

Identifiers

PMID36800233
PMCPMC10008499
OpenAlexW4321168331

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read62
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.