Evidence map›Paper›PMID 36800152›Full record

ReviewAmerican journal of clinical dermatology2023

Stasis Dermatitis: An Overview of Its Clinical Presentation, Pathogenesis, and Management.

Gil Yosipovitch, Susan T Nedorost, Jonathan I Silverberg, Adam J Friedman, Juliana M Canosa, Amy Cha

Open access · hybridAbstract readReview
In one paragraph

Review in American journal of clinical dermatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
16.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
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  17. Novel drug delivery systems in topical treatment of atopic dermatitis.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Gil YosipovitchMiami Itch Center, Miller School of Medicine, University of Miami, Miami, FL, USA.
Susan T NedorostUniversity Hospitals of Cleveland, Cleveland, OH, USA.
Jonathan I SilverbergThe George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Adam J FriedmanGW Medical Faculty Associates, NW, Washington, DC, USA.
Juliana M CanosaPfizer Brasil Ltda., São Paulo, SP, Brazil. juliana.machadocanosa@pfizer.com.ORCID http://orcid.org/0000-0002-2095-5096
Amy ChaPfizer Inc., New York, NY, USA.
Pfizer (United States) · USGeorge Washington University · USGW Medical Faculty Associates · USUniversity Hospitals of Cleveland · USUniversity of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stasis dermatitis is a chronic inflammatory skin disease of the lower extremities. It typically occurs in older individuals and is the cutaneous manifestation of venous hypertension caused by venous reflux. Such retrograde venous blood flow is the result of incompetent venous valves, valve destruction, or venous obstruction. Stasis dermatitis is eczematous. The associated impairment of venous valves may cause swelling of the legs, leading to serious conditions including venous ulcerations. Diagnosis can be challenging because of its clinical resemblance to other skin conditions and poor clinical recognition by physicians. The cornerstones of stasis dermatitis treatment are compression therapy to ameliorate pain and swelling, topical treatments to alleviate secondary skin changes, and interventional treatment options to correct the underlying causes of venous reflux. Given the central role of inflammation of the lower extremities in driving the cutaneous changes characteristic of stasis dermatitis, new therapeutic approaches that target the inflammation are under clinical evaluation in patients with stasis dermatitis.

Indexed as

EczemaLeg DermatosesVaricose UlcerVaricose VeinsVenous InsufficiencyAgedHumansInflammation

Identifiers

PMID36800152
PMCPMC9968263
OpenAlexW4321166002

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.