Evidence map›Paper›PMID 36800139›Full record

ArticleInternational urology and nephrology2023

Acute kidney injury in neurocritical patients: a retrospective cohort study.

Gonzalo Ramírez-Guerrero, Cristian Lucero, Francisco Villagrán-Cortés, Ernesto Hauway, Vicente Torres-Cifuentes, Romyna Baghetti-Hernández, Aldo Vera-Calzaretta, Claudio Ronco, Osvaldo Garay

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Article in International urology and nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  6. Acute kidney injury in neurocritical care.Critical care (London, England) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gonzalo Ramírez-GuerreroCritical Patients Unit, Carlos Van Buren Hospital, San Ignacio #725, Valparaiso, Chile. gonzalo.ramirezg@redsalud.gob.cl.ORCID http://orcid.org/0000-0002-1696-9997
Cristian LuceroCritical Patients Unit, Carlos Van Buren Hospital, San Ignacio #725, Valparaiso, Chile.
Francisco Villagrán-CortésCritical Patients Unit, Carlos Van Buren Hospital, San Ignacio #725, Valparaiso, Chile.
Ernesto HauwayCritical Patients Unit, Carlos Van Buren Hospital, San Ignacio #725, Valparaiso, Chile.
Vicente Torres-CifuentesCritical Patients Unit, Carlos Van Buren Hospital, San Ignacio #725, Valparaiso, Chile.
Romyna Baghetti-HernándezCritical Patients Unit, Carlos Van Buren Hospital, San Ignacio #725, Valparaiso, Chile.
Aldo Vera-CalzarettaDepartamento de Kinesiología, Facultad de Ciencias de la Salud, Universidad de Atacama, Copiapó, Chile.
Claudio RoncoDepartment of Nephrology, Dialysis and Kidney Transplantation, San Bortolo Hospital, Vicenza, Italy.
Osvaldo GarayCritical Patients Unit, Carlos Van Buren Hospital, San Ignacio #725, Valparaiso, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND /

objectiveAcute kidney injury (AKI) is a significant complication in critical care units (CCU). Non-neurological complications such as AKI are an independent predictor of poor clinical outcomes, with an increase in morbidity and mortality, financial costs, and worse functional recovery. This work aims to estimate the incidence of AKI and evaluate the risk factors and complications of AKI in neurocritical patients hospitalized in the CCU.

methodsA retrospective cohort study was conducted. Patients admitted to the neurocritical care unit between 2016 and 2018 with a stay longer than 48 h were retrospectively analyzed in regard to the incidence, risk factors, and outcomes of AKI.

resultsThe study population comprised 213 neurocritical patients. The incidence of AKI was 23.5%, with 58% KDIGO 1 and 2% requiring renal replacement therapy. AKI was an independent predictor of prolonged use of mechanical ventilation, cerebral edema, and mortality. Cerebral edema [OR 4.40 (95% CI 1.98-9.75) p < 0.001] and a change in chloride levels greater than 4 mmol/L at 48 h (OR 2.44 (95% CI 1.10-5.37) p = 0.027) were risk factors for developing AKI in the first 14 days of hospitalization.

conclusionThere is a high incidence of AKI in neurocritical patients; it is associated with worse clinical outcomes regardless of the CCU admission etiology or AKI severity.

Indexed as

Acute Kidney InjuryBrain EdemaHospital MortalityHumansIncidenceIntensive Care UnitsRetrospective StudiesRisk FactorsAcute kidney injuryCerebral hemorrhageCritical careStrokeSubarachnoid hemorrhageTraumatic brain injury

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.