Evidence map›Paper›PMID 36800127›Full record

ArticleAnnals of surgical oncology2023

Robot-Assisted Versus Laparoscopic Distal Pancreatectomy in Patients with Resectable Pancreatic Cancer: An International, Retrospective, Cohort Study.

Jeffrey W Chen, Tess M E van Ramshorst, Sanne Lof, Bilal Al-Sarireh, Bergthor Bjornsson, Ugo Boggi, Fernando Burdio, Giovanni Butturini, Riccardo Casadei, Andrea Coratti and 29 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Annals of surgical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.

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  8. Pancreatic cancer in 2025: Have we found a solution?World journal of gastroenterology · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

39 authors at 20 institutions in 10 countries.

Jeffrey W Chen *Amsterdam UMC, Department of Surgery, Location University of Amsterdam, Amsterdam, The Netherlands.
Tess M E van Ramshorst *Amsterdam UMC, Department of Surgery, Location University of Amsterdam, Amsterdam, The Netherlands.
Sanne LofAmsterdam UMC, Department of Surgery, Location University of Amsterdam, Amsterdam, The Netherlands.
Bilal Al-SarirehDepartment of Surgery, Morriston Hospital, Swansea, UK.
Bergthor BjornssonDepartment of Surgery and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Ugo BoggiDepartment of Surgery, University Hospital of Pisa, Pisa, Italy.
Fernando BurdioDepartment of Surgery, University Hospital del Mar, Barcelona, Spain.
Giovanni ButturiniDepartment of Surgery, Pederzoli Hospital, Peschiera, Italy.
Riccardo CasadeiDepartment of Surgery, Sant'Orsola Malphigi Hospital, Bologna, Italy.
Andrea CorattiDivision of Oncological and Robotic General Surgery, Careggi University Hospital, Florence, Italy.
Mathieu D'HondtDepartment of Digestive and Hepatobiliary/Pancreatic Surgery, Groeninge Hospital, Kortrijk, Belgium.
Safi DokmakDepartment of HPB Surgery and Liver Transplantation, Beaujon Hospital, Clichy, France.
Bjørn EdwinThe Intervention Center, Department of Surgery, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Alessandro EspositoDepartment of General and Pancreatic Surgery, Pancreas Institute, Verona University Hospital, Verona, Italy.
Jean M FabreDepartment of Surgery, Saint-Éloi Hospital, Montpellier, France.
Giovanni FerrariDepartment of Surgery, Niguarda Hospital, Milan, Italy.
Fadhel S FtéricheDepartment of HPB Surgery and Liver Transplantation, Beaujon Hospital, Clichy, France.
Giuseppe K FusaiHPB & Liver Transplant Unit, Royal Free London, London, UK.
Bas Groot KoerkampDepartment of Surgery, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Thilo HackertDepartment of Surgery, Heidelberg University Hospital, Heidelberg, Germany.
Asif JahDepartment of HPB Surgery and Transplantation, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Jin-Young JangDepartment of Surgery, Seoul National University Hospital, Seoul, South Korea.
Emanuele F KauffmannDepartment of Surgery, University Hospital of Pisa, Pisa, Italy.
Tobias KeckDepartment of Surgery, University Medical Center Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
Alberto ManzoniDepartment of General Surgery, Istituto Ospedaliero Fondazione Poliambulanza, Brescia, Italy.
Marco V MarinoDepartment of Emergency and General Surgery, Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy.
Quintus MolenaarDepartment of Surgery, UMC Utrecht Cancer Center, University Medical Center Utrecht, Utrecht, The Netherlands.
Elizabeth PandoDepartment of Surgery, Vall d'Hebron University Hospital, Barcelona, Spain.
Patrick PessauxDepartment of Hepato-Biliary and Pancreatic Surgery, Nouvel Hôpital Civil, Institut Hospitalo-Universitaire de Strasbourg, Strasbourg, France.
Andrea PietrabissaDepartment of Surgery, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Zahir SoonawallaDepartment of Surgery, Oxford University Hospital, Oxford, UK.
Robert P SutcliffeDepartment of Hepato-Pancreato-Biliary and Liver Transplant Surgery, Queen Elizabeth University Hospitals Birmingham, Birmingham, UK.
Lea TimmermannDepartment of Surgery, Charité, Berlin, Germany.
Steven WhiteDepartment of Surgery, The Freeman Hospital, Newcastle Upon Tyne, Newcastle, UK.
Vincent S YipDepartment of HPB Surgery, The Royal London Hospital, Bartshealth NHS Trust, London, UK.
Alessandro ZerbiDepartment of Surgery, Humanitas University and IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
Mohammad Abu Hilal *Department of General Surgery, Istituto Ospedaliero Fondazione Poliambulanza, Brescia, Italy. abuhilal9@gmail.com.
Marc G Besselink *Amsterdam UMC, Department of Surgery, Location University of Amsterdam, Amsterdam, The Netherlands. m.g.besselink@amsterdamUMC.nl.
European Consortium on Minimally Invasive Pancreatic Surgery (E-MIPS)
Cancer Center Amsterdam · NLHôpital Beaujon · FRAzienda Ospedaliera Universitaria Pisana · ITCambridge University Hospitals NHS Foundation Trust · GBCharité - Universitätsmedizin Berlin · DEFondazione Poliambulanza Istituto Ospedaliero · ITFreeman Hospital · GBHospital Del Mar · ESIRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITQueen Elizabeth University Hospital · GBAmsterdam University Medical Centers · NLAZ Groeninge · BEAzienda Ospedaliero-Universitaria Careggi · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITBarts Health NHS Trust · GBErasmus MC Cancer Institute · NLHeidelberg University · DEHôpital Civil, Strasbourg · FRHôpital Saint Eloi · FRHumanitas University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRobot-assisted distal pancreatectomy (RDP) is increasingly used as an alternative to laparoscopic distal pancreatectomy (LDP) in patients with resectable pancreatic cancer but comparative multicenter studies confirming the safety and efficacy of RDP are lacking.

methodsAn international, multicenter, retrospective, cohort study, including consecutive patients undergoing RDP and LDP for resectable pancreatic cancer in 33 experienced centers from 11 countries (2010-2019). The primary outcome was R0-resection. Secondary outcomes included lymph node yield, major complications, conversion rate, and overall survival.

resultsIn total, 542 patients after minimally invasive distal pancreatectomy were included: 103 RDP (19%) and 439 LDP (81%). The R0-resection rate was comparable (75.7% RDP vs. 69.3% LDP, p = 0.404). RDP was associated with longer operative time (290 vs. 240 min, p < 0.001), more vascular resections (7.6% vs. 2.7%, p = 0.030), lower conversion rate (4.9% vs. 17.3%, p = 0.001), more major complications (26.2% vs. 16.3%, p = 0.019), improved lymph node yield (18 vs. 16, p = 0.021), and longer hospital stay (10 vs. 8 days, p = 0.001). The 90-day mortality (1.9% vs. 0.7%, p = 0.268) and overall survival (median 28 vs. 31 months, p = 0.599) did not differ significantly between RDP and LDP, respectively.

conclusionsIn selected patients with resectable pancreatic cancer, RDP and LDP provide a comparable R0-resection rate and overall survival in experienced centers. Although the lymph node yield and conversion rate appeared favorable after RDP, LDP was associated with shorter operating time, less major complications, and shorter hospital stay. The specific benefits associated with each approach should be confirmed by multicenter, randomized trials.

Indexed as

LaparoscopyPancreatic NeoplasmsRoboticsRobotic Surgical ProceduresCohort StudiesHumansLength of StayOperative TimePancreatectomyRetrospective StudiesTreatment Outcome

Identifiers

PMID36800127
PMCPMC10085922
OpenAlexW4321162933

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.