Evidence map›Paper›PMID 36800112›Full record

ArticleLa Radiologia medica2023

Diagnostic performance of deep learning-based vessel extraction and stenosis detection on coronary computed tomography angiography for coronary artery disease: a multi-reader multi-case study.

Wenjie Yang, Chihua Chen, Yanzhao Yang, Lei Chen, Changwei Yang, Lianggeng Gong, Jianing Wang, Feng Shi, Dijia Wu, Fuhua Yan

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In one paragraph

Article in La Radiologia medica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Wenjie Yang *Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chihua Chen *Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yanzhao YangDepartment of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lei ChenDepartment of Radiology, Peking University People's Hospital, Beijing, China.
Changwei YangDepartment of Radiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Lianggeng GongDepartment of Radiology, Second Affiliated Hospital of Nanchang University, Nanchang, China.
Jianing WangDepartment of Radiology, Affiliated Hospital of Hebei University, Baoding, China.
Feng ShiShanghai United Imaging Intelligence Co., Ltd, Shanghai, China.
Dijia WuShanghai United Imaging Intelligence Co., Ltd, Shanghai, China.
Fuhua YanDepartment of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. yfh11655@rjh.com.cn.ORCID http://orcid.org/0000-0002-5910-1506
Shanghai Jiao Tong University · CNUnited Imaging Healthcare (China) · CNAffiliated Hospital of Hebei University · CNNanchang University · CNPeking University · CNShanghai East Hospital · CN

Funding

Natural Science Foundation of Shanghai 8217070113
6 · The paper itself

Abstract

backgroundPost-processing and interpretation of coronary CT angiography (CCTA) imaging are time-consuming and dependent on the reader's experience. An automated deep learning (DL)-based imaging reconstruction and diagnosis system was developed to improve diagnostic accuracy and efficiency.

methodsOur study including 374 cases from five sites, inviting 12 radiologists, assessed the DL-based system in diagnosing obstructive coronary disease with regard to diagnostic performance, imaging post-processing and reporting time of radiologists, with invasive coronary angiography as a standard reference. The diagnostic performance of DL system and DL-assisted human readers was compared with the traditional method of human readers without DL system.

resultsComparing the diagnostic performance of human readers without DL system versus with DL system, the AUC was improved from 0.81 to 0.82 (p < 0.05) at patient level and from 0.79 to 0.81 (p < 0.05) at vessel level. An increase in AUC was observed in inexperienced radiologists (p < 0.05), but was absent in experienced radiologists. Regarding diagnostic efficiency, comparing the DL system versus human reader, the average post-processing and reporting time was decreased from 798.60 s to 189.12 s (p < 0.05). The sensitivity and specificity of using DL system alone were 93.55% and 59.57% at patient level and 83.23% and 79.97% at vessel level, respectively.

conclusionsWith the DL system serving as a concurrent reader, the overall post-processing and reading time was substantially reduced. The diagnostic accuracy of human readers, especially for inexperienced readers, was improved. DL-assisted human reader had the potential of being the reading mode of choice in clinical routine.

Indexed as

Coronary Artery DiseaseCoronary StenosisDeep LearningComputed Tomography AngiographyConstriction, PathologicCoronary AngiographyHumansCoronary CT angiography (CCTA)Deep learning (DL)

Identifiers

PMID36800112
OpenAlexW4321166969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.