Evidence map›Paper›PMID 36800063›Full record

SynthesisLasers in medical science2023

Laser and light therapy combined with topical minoxidil for alopecia areata: a systematic review and meta-analysis of randomized controlled trials.

Jianfeng Zhang, Peng Lin, Haiyue Lin, Cong Ma, Yi Hu, Yingdong Wang, Yu Zhang

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Lasers in medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. S3 guideline diagnostics and therapy in alopecia areata - Part 2: Therapy, psychosocial and cosmetic support.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
    Guideline
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Alopecia Areata: An Updated Review for 2023.Journal of cutaneous medicine and surgery
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jianfeng Zhang *Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Peng Lin *Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Haiyue LinGraduate School, Tianjin Medical University, Tianjin, 300070, China.
Cong MaGraduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Yi HuGraduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Yingdong WangGraduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Yu ZhangDepartment of Dermatology, Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, 300120, China. niuniuzy7375@aliyun.com.ORCID http://orcid.org/0000-0001-9317-2466
Tianjin University of Traditional Chinese Medicine · CNTianjin Medical University · CN

Funding

Tianjin Municipal Health Commission Health Science and Technology Project zc20129Tianjin Municipal Health Commission Research Project of Western and Integrative Medicine 2021001Tianjin Municipal Health Commission Research Projects in Key Areas of Traditional Chinese Medicine 2019002
6 · The paper itself

Abstract

We aim to evaluate the clinical efficacy and safety of using laser and light combined with topical minoxidil for alopecia areata. We searched PubMed, Embase, Web of Science, the Cochrane Library, China National Knowledge Infrastructure (CNKI), China Biomedical Literature Database (CBM), VIP database, and Wanfang Data from their inception to September 18, 2022. The risk of bias of the included RCTs was assessed by the Cochrane Collaboration tool. RevMan 5.3 software and Stata 14.0 software were used to perform the statistical analysis. The GRADE system assessed the quality of evidence. Ten studies were enrolled finally. The results of the meta-analysis showed that compared with topical minoxidil alone, the 308-nm excimer laser/light or He-Ne laser combined with topical minoxidil could reduce the SALT (Severity of Alopecia Tool) score (MD= -5.88, 95% CI [-9.79, -1.98], P=0.003). Whether fractional CO

Indexed as

Alopecia AreataMinoxidilHumansLasersPhototherapyRandomized Controlled Trials as TopicMinoxidilAlopecia areataLaserLight therapyMeta-analysisMinoxidilSystematic review

Identifiers

PMID36800063
OpenAlexW4321172387

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.