Observational studyClinical oral investigations2023
Relationship of obstructive sleep apnea with periodontal condition and its local and systemic risk factors.
Observational study in Clinical oral investigations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Obstructive sleep apnea and periodontitis: a systematic review with considerations on CPAP therapy.Acta odontologica Scandinavica · 2026Pooled it
- Association Between Obstructive Sleep Apnea and Periodontitis: A Systematic Umbrella Review.Clinical and experimental dental research · 2026Pooled it
- Clinical Insights Regarding Oral Health Among Untreated and Positive Airway Pressure Treated Obstructive Sleep Apnea Patients.Journal of sleep research · 2026Article
- Periodontal disease and obstructive sleep apnea: an umbrella review.Frontiers in oral health · 2026Review
- Hidden oral inflammation and biomarker misclassification in obstructive sleep apnea trials.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Interdisciplinary Perspectives on Dentistry and Sleep Medicine: A Narrative Review of Sleep Apnea and Oral Health.Journal of clinical medicine · 2025Review
- Central adiposity indices and inflammatory markers mediate the association between life's crucial 9 and periodontitis in US adults.Lipids in health and disease · 2025Article
- Alterations of the salivary microbiome in obstructive sleep apnea and their association with periodontitis.Frontiers in cellular and infection microbiology · 2025Article
- Sleep disorders as independent predictors of taste dysfunction risk.BMC oral health · 2024Article
- Sleep and periodontal health.Periodontology 2000 · 2024Review
- Periodontitis associated with risk of obstructive sleep apnea in Peruvian adult patients: A cross-sectional study.Medicina oral, patologia oral y cirugia bucal · 2024Observational
- Oral Health Implications of Obstructive Sleep Apnea: A Literature Review.Biomedicines · 2024Review
- Clinical and radiographic periodontal status in hypertensive patients with or without obstructive sleep apnea 10 years after diagnosis and CPAP initiation.Clinical and experimental dental research · 2024Article
- Association between hypothyroidism and obstructive sleep apnea: a bidirectional Mendelian randomization study combined with the geo database.Frontiers in neurology · 2024Article
- Severe Chronic Gingivitis in Association With Hypothyroidism and Grade 2 Adenoid Hypertrophy: A Case Report.Cureus · 2023Article
- Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveObstructive sleep apnea (OSA) and periodontitis share risk factors, such as age, obesity, stress, and cardiovascular events, which have a bidirectional cause-effect relationship through systemic inflammation. Our objective was to determine the relationship between OSA and the periodontal condition and its associated local and systemic risk factors. MATERIAL AND
methodsThis was an observational case-control study involving 60 patients. Local oral risk factors and the systemic condition of each patient were evaluated. All patients underwent polysomnography for the diagnosis of OSA. Chi-squared, one-way ANOVA, and Bonferroni's tests were performed.
resultsA higher percentage of patients with periodontitis had severe OSA (66.66%); however, no statistically significant association was found between the two pathologies (p = 0.290). In terms of systemic risk factors, an association was found between arterial hypertension and severe OSA (p = 0.038), and in terms of local factors, an association was found between the use of removable prostheses and severe OSA (p = 0.0273).
conclusionIn the general population, patients with periodontitis showed a higher prevalence of severe OSA. Obesity and hypothyroidism were the most prevalent systemic findings in patients with OSA and periodontitis. Arterial hypertension and osteoarthritis were found to be associated with severe OSA. The local risk factors associated with periodontitis and severe OSA were removable partial dentures and misfit resins. CLINICAL RELEVANCE: To study the factors that can facilitate the progression of OSA and periodontitis, physicians and dentists should be advised to provide comprehensive care for patients with both pathologies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.