ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2023
Opportunistic measures of bone mineral density at multiple skeletal sites during whole-body CT in polytrauma patients.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- What can we learn about bone density in COPD patients from a chest CT? A systematic review.Croatian medical journal · 2024Pooled it
- CT-derived adrenal-to-spleen ratio as a predictor of massive transfusion and mortality in emergency transcatheter arterial embolization of active bleeding.Emergency radiology · 2026Article
- Heterogeneity in Lumbar Segmental Bone Mineral Density and Age-Related Evolution of Whole-Body Bone Mineral Density: Comprehensive Implications for Osteoporosis Risk Assessment.Orthopaedic surgery · 2026Article
- Osteoporosis screening and major osteoporotic fracture prediction by cranial computed tomography-derived Hounsfield units: a multi-center study on opportunistic osteoporosis screening.Annals of medicine · 2025Article
- Utility of clavicle cortex index as a screening tool for low bone mineral density.Scientific reports · 2025Article
- The utility of computed tomography-derived inferior vena cava parameters in predicting outcomes in patients with active bleeding undergoing transarterial embolization.International journal of emergency medicine · 2025Article
- Evaluation and analysis of risk factors for fractured vertebral recompression post-percutaneous kyphoplasty: a retrospective cohort study based on logistic regression analysis.BMC musculoskeletal disorders · 2025Article
- Opportunistic screening for osteoporosis using routine clinical care computed tomography brain studies.Skeletal radiology · 2025Article
- Prognostic significance of inferior vena cava volume defined by initial polytrauma CT-imaging: single-center experience of a level-1 trauma center.International journal of emergency medicine · 2024Article
- Evaluation and analysis of risk factors for adverse events of the fractured vertebra post-percutaneous kyphoplasty: a retrospective cohort study using multiple machine learning models.Journal of orthopaedic surgery and research · 2024Article
- Coronary artery calcification detected by initial polytrauma CT in severely injured patients: retrospective single-center cohort study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- Is Type and Grade of Emphysema Important for Bone Mineral Density and Aortic Calcifications?Journal of clinical medicine · 2024Article
- Semi-automatic proximal humeral trabecular bone density assessment tool: technique application and clinical validation.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024Article
- A diagnostic approach integrated multimodal radiomics with machine learning models based on lumbar spine CT and X-ray for osteoporosis.Journal of bone and mineral metabolism · 2023Article
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Abstract
Whole-body CT in polytrauma patients revealed bone mineral density variations throughout the skeleton. Bone density was the highest in cranial bones and the lowest in proximal extremities and pelvis. Skeletal age-related changes were generally more pronounced than sex-related changes. Cranial bones did not follow the same aging pattern compared to other bones.
introductionWhole-body CT (WBCT) in polytrauma patients enables the detection of numerous incidental findings, such as estimates of bone mineral density (BMD) at multiple skeletal sites. This could help in better understanding of age- and sex-related changes in BMD through skeleton.
methodsData were retrospectively retrieved from the WBCTs requested during a 2-year period. BMD, expressed in CT Hounsfield units (HU), was measured at frontal and occipital bone, four vertebrae (C4, Th7, L4, and S2), iliac bone, and proximal humerus and femur. Measurements were done on native and postcontrast scans. The population sample was age-, sex-, and visceral fat volume adjusted for analysis.
resultsA total of 296 patients were included, with a median age of 51 years. BMD varied from the highest HU in cranial bones (629 HU) to the lowest HU in the pelvic bones (114 HU), P < 0.001. Sex differences were independent predictors of BMD in cranial bones and proximal humerus. The age-related decline in BMD was significant in all other bones, but the association with age differed among the measurement's sites. Visceral fat showed the strongest correlation with the lumbar spine and iliac wing, although multivariate analysis revealed it was not an independent predictor of bone density, such as age and sex.
conclusionsBMD varies through skeleton, being the highest in the proximal axial skeleton. Age-related changes in BMD are significant and more pronounced than sex-related changes in almost all bones. Cranial bones do not follow the same pattern compared to other bones.
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