Evidence map›Paper›PMID 36799975›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2023

The association between COVID-19 vaccination and idiopathic sudden sensorineural hearing loss, clinical manifestation and outcomes.

Ran Fisher, Yehuda Tarnovsky, Nir Hirshoren, Michal Kaufman, Sagit Stern Shavit

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. COVID-19 vaccination and idiopathic sudden sensorineural hearing loss: comment.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Ran FisherDepartment of Otolaryngology, Head and Neck Surgery (HNS), Hadassah Medical Center and the Hebrew University School of Medicine, Ein-Kerem, 91120, Jerusalem, Israel.ORCID http://orcid.org/0000-0001-7025-7969
Yehuda TarnovskyDepartment of Otolaryngology-Head and Neck Surgery, Shaare Zedek Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.ORCID http://orcid.org/0000-0001-5088-9862
Nir HirshorenDepartment of Otolaryngology, Head and Neck Surgery (HNS), Hadassah Medical Center and the Hebrew University School of Medicine, Ein-Kerem, 91120, Jerusalem, Israel.ORCID http://orcid.org/0000-0002-5601-8336
Michal KaufmanDepartment of Otolaryngology, Head and Neck Surgery (HNS), Hadassah Medical Center and the Hebrew University School of Medicine, Ein-Kerem, 91120, Jerusalem, Israel.ORCID http://orcid.org/0000-0003-0004-1024
Sagit Stern ShavitDepartment of Otolaryngology, Head and Neck Surgery (HNS), Hadassah Medical Center and the Hebrew University School of Medicine, Ein-Kerem, 91120, Jerusalem, Israel. sagitsternshavit@gmail.com.ORCID http://orcid.org/0000-0003-1675-8644

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePrevious data demonstrated an increased incidence of Idiopathic Sensorineural Hearing Loss (ISSNHL) in 2021 compared to 2019-2020, suggesting an association with the anti-COVID-19 vaccine. We aimed to assess our center's incidence and compare the clinical manifestations and outcomes of vaccinated vs. unvaccinated patients.

methodsA retrospective chart review of all patients diagnosed with ISSNHL during 2021 was conducted and compared to patients who presented in 2018-2020. Patient demographics, audiometry features, vaccination status, and prognosis were evaluated.

resultsThroughout 2021, 51 patients were diagnosed with ISSNHL, compared with 31 during 2020, 38 in 2019, and 41 in 2018, demonstrating a 64%, 34%, and 24% increase, respectively. Among patients who presented in 2021, 13 (25.4%) received the anti-COVID-19 vaccine within 30 days before their presentation, and 4 received it within 96 h. Most presented after receiving the second or third dose. Patient characteristics, audiometry features, and prognosis did not significantly differ between vaccinated and unvaccinated patients.

conclusionsA marked incline was seen in the 2021 ISSNHL incidence at our medical center, of which 25% of cases were within a month post-anti-COVID-19 vaccination. No significant difference was found in clinical manifestations and outcomes between vaccinated and nonvaccinated patients. While other justifications could be sought, an association cannot be ruled out, and further research is needed.

Indexed as

COVID-19Hearing Loss, SensorineuralHearing Loss, SuddenVaccinesHumansPrognosisRetrospective StudiesVaccinesCOVID-19mRNA-based vaccinesPfizer-BioNTech COVID-19 vaccineSudden sensorineural hearing loss

Identifiers

PMID36799975
PMCPMC9936109

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.