Evidence map›Paper›PMID 36799163›Full record

ArticleMolecular medicine reports2023

Maltol inhibits oxygen glucose deprivation‑induced chromatinolysis in SH‑SY5Y cells by maintaining pyruvate level.

Shuyan Zhang, Xinyue Zhang, Xuanzhong Wang, Chen Li, Chuan He, Tianfei Luo, Pengfei Ge

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular medicine reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Shuyan ZhangDepartment of Neurotrauma, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Xinyue ZhangDepartment of Public Health, New York University, New York, NY 10016, USA.
Xuanzhong WangDepartment of Neurosurgery, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Chen LiDepartment of Neurosurgery, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Chuan HeDepartment of Neurotrauma, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Tianfei LuoResearch Center of Neuroscience, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Pengfei GeDepartment of Neurosurgery, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Jilin University · CNNew York University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maltol, a chemical isolated from ginseng root, has shown treatment effects on several pathological processes including osteoarthritis, diabetic peripheral neuropathy and liver fibrosis. Nevertheless, its effect on ischemia‑induced neuron death remains elusive. In the present study, the treatment effect of maltol on ischemia‑induced neuron damage was investigated by using oxygen and glucose deprivation (OGD) model in SH‑SY5Y cells.

Indexed as

NeuroblastomaOxygenCatalaseGlucoseHumansPyronesPyruvic AcidReactive Oxygen SpeciesTOR Serine-Threonine KinasesCatalaseGlucosemaltolOxygenPyronesPyruvic AcidReactive Oxygen SpeciesTOR Serine-Threonine Kinasesapoptosis inducing factorchromatinolysisglycolysismaltoloxygen glucose deprivation

Identifiers

PMID36799163
PMCPMC9950851
OpenAlexW4320920912

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.