Evidence map›Paper›PMID 36798925›Full record

ArticleAdvanced biomedical research2022

Effects of Methadone on the Toll-like Receptor 4 Expression in Human Non-Small Cell Lung Carcinoma A549 Cell Line Using

Golnaz Vaseghi, Nastaran Rashidi, Nasrin Zare, Fahimeh Ghasemi, Marjan Pourhadi, Laleh Rafiee, Shaghayegh Haghjooy Javanmard

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced biomedical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Golnaz VaseghiIsfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Nastaran RashidiDepartment of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Nasrin ZareApplied Physiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Fahimeh GhasemiDepartment of Bioinformatics and Systems Biology, School Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Marjan PourhadiDepartment of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Laleh RafieeDepartment of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Shaghayegh Haghjooy JavanmardDepartment of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Isfahan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In this study, the effects of methadone and naloxone on the expression of toll-like receptor 4 ( Materials and Methods: Lung cancer A549 cell cultures were stimulated for 24 h with methadone (5, 10, and 20 μM) and naloxone (20 and 40 μM) concentrations. The level of Results: Migration rate of the A549 cells treated with 5 ( Conclusion: According to the present DATA, methadone affects the

Indexed as

A549 cellslung cancermethadonenaloxonetoll-like receptor 4

Identifiers

PMID36798925
PMCPMC9926039
OpenAlexW4313000067

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.