Evidence map›Paper›PMID 36798768›Full record

ReviewHeliyon2023

Expression, regulating mechanism and therapeutic target of KIF20A in multiple cancer.

Zheng Jin, Fei Peng, Chao Zhang, Shuang Tao, Damo Xu, Zhenhua Zhu

Open access · goldAbstract readReview
In one paragraph

Review in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 55 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Zheng JinDepartment of Respirology & Allergy, The Third Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong Province, China.
Fei PengDepartment of Medicine, Division of Endocrinology, Diabetes and Metabolism, Baylor College of Medicine, Houston, Texas, USA.
Chao ZhangGuangzhou Women and Children's Medical Center, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Shuang TaoDepartment of Otorhinolaryngology Head and Neck Surgery, Longgang Central Hospital of Shenzhen, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Damo XuDepartment of Respirology & Allergy, The Third Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong Province, China.
Zhenhua ZhuDepartment of Orthopaedic Trauma, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong Province, China.
Shenzhen University · CNBaylor College of Medicine · USGuangzhou Medical University · CNGuangzhou University of Chinese Medicine · CNThird Affiliated Hospital of Southern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kinesin family member 20A (KIF20A) is a member of the kinesin family. It transports chromosomes during mitosis, plays a key role in cell division. Recently, studies proved that KIF20A was highly expressed in cancer. High expression of KIF20A was correlated with poor overall survival (OS). In this review, we summarized all the cancer that highly expressed KIF20A, described the role of KIF20A in cancer. We also organized phase I and phase II clinical trials of KIF20A peptides vaccine. All results indicated that KIF20A was a promising therapeutic target for multiple cancer.

Indexed as

ATP, adenosine triphosphateBTC, biliary tract cancerCancerCdk1, cyclin-dependent kinase 1circRNA, circular RNACPC, chromosomal passenger complexCTL, cytotoxic T lymphocyteDLG5, discs large MAGUK scaffold protein 5EMT, epithelial-mesenchymal transitionExpressionFoxM1, forkhead box protein M1GC, gastric cancerGEM, gemcitabineGli2, glioma-associated oncogene 2HLA, human leukocyte antigenHNMT, head-and-neck malignant tumorIRF, interferon regulatory factorJAK, Janus kinaseKIF20AKIF20A, kinesin family member 20ALP, long peptideMad2, mitotic arrest deficient 2MHC I, major histocompatibility complex ImiRNA, microRNAMKlp2, mitotic kinesin-like protein 2OS, overall survivalPBMC, peripheral blood mononuclear cellPlk1, polo-like kinase 1Regulating mechanismsTherapeutic target

Identifiers

PMID36798768
PMCPMC9925975
OpenAlexW4319064018

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.