Evidence map›Paper›PMID 36798758›Full record

ArticleHeliyon2023

Fabrication of polycaprolactone/calcium phosphates hybrid scaffolds impregnated with plant extracts using 3D printing for potential bone regeneration.

Claudia Garcia, Yeison Orozco, Alejandra Betancur, Ana Isabel Moreno, Katherine Fuentes, Alex Lopera, Oscar Suarez, Tatiana Lobo, Alexander Ossa, Alejandro Peláez-Vargas and 1 more

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Electrospun Fibers EncapsulatingMolecules (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Claudia GarciaUniversidad Nacional de Colombia sede Medellín, Physics school, Grupo de Materiales Cerámicos y Vítreos, Colombia.
Yeison OrozcoUniversidad Nacional de Colombia sede Medellín, Grupo de Materiales Cerámicos y Vítreos, Colombia.
Alejandra BetancurUniversidad Nacional de Colombia sede Medellín, Grupo de Materiales Cerámicos y Vítreos, Colombia.
Ana Isabel MorenoUniversidad Nacional de Colombia sede Medellín, Grupo de Materiales Cerámicos y Vítreos, Colombia.
Katherine FuentesUniversidad Nacional de Colombia sede Medellín, Colombia.
Alex LoperaGrupo de Nanoestructuras y Física Aplicada (NANOUPAR), Dirección Académica, Universidad Nacional de Colombia, Sede de La Paz, Km 9 vía Valledupar La Paz, La Paz 202010, Colombia.
Oscar SuarezUniversidad Nacional de Colombia sede Orinoquia, Colombia.
Tatiana LoboUniversidad Nacional de Colombia sede Medellín, Chemistry school, Colombia.
Alexander OssaSchool of Applied Sciences and Engineering, Universidad Eafit, Medellín, Colombia.
Alejandro Peláez-VargasUniversidad Cooperativa de Colombia, Medellín, Colombia.
Carlos PaucarUniversidad Nacional de Colombia sede Medellín, Chemistry school, Grupo de Materiales Cerámicos y Vítreos, Colombia.
Universidad Nacional de Colombia · COUniversidad Cooperativa de Colombia · COUniversidad EAFIT · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increase in critical bone diseases and defects in the world's population increases the need for bone substitutes to restore form and function. Organic and inorganic scaffolds with antibacterial properties could provide advantages for bone regeneration. In this study, we obtained scaffolds of polycaprolactone (PCL) charged with calcium phosphates nanoparticles and impregnated with extracts of Colombian plants as an alternative for potential bone regeneration. Calcium phosphate nanoparticles were obtained via auto-combustion synthesis. The nanoparticles were incorporated into the PCL with a chemical dissolution-disperse process. The composite obtained was used to produce a filament to print Triply Periodic Minimal Surface (TPMS) based scaffolds. Such geometry facilitates cellular growth thanks to its interconnected porosity. The scaffolds were impregnated with extracts of

Indexed as

3-D printingCalcium phosphateImpregnation methodNatural extractsPolycaprolactoneScaffold

Identifiers

PMID36798758
PMCPMC9925874
OpenAlexW4319064014

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.