Evidence map›Paper›PMID 36798521›Full record

ArticleFrontiers in immunology2022

Endoscopic retrograde appendicitis therapy in the management of chronic fecalith appendicitis in a patient with ulcerative colitis: The first human case report.

Muhammad Zulqarnain, Guangxing Cui, Wen Lyu, Haitao Huang, Xia Wang, Hamse Mohamoud Abdi, Lingfei Gu, Shijie Fang, Fangzhou Liu, Liqian Ling

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 7 citations in OpenAlex.

  1. Appendix in ulcerative colitis pathogenesis and therapy: An updated narrative review.World journal of gastrointestinal pathophysiology · 2026
    Review
  2. Relationship between the appendix and ulcerative colitis: A new discovery.World journal of gastrointestinal endoscopy · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Myeloid-derived suppressor cells modulation in the context of tumor microenvironment for gastric cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  7. Combining NAD(P)H-FLIM and PLIM of Ir5 pH sensor to optimize photodynamic therapy through metabolic intracellular pattern segmentation.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Endoscopic retrograde appendicitis therapy.Therapeutic advances in gastroenterology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Muhammad ZulqarnainDepartment of Gastroenterology, Fourth Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, China.
Guangxing CuiDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Wen LyuDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Haitao HuangDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Xia WangDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Hamse Mohamoud AbdiDepartment of Gastroenterology, Fourth Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, China.
Lingfei GuDepartment of Gastroenterology, Fourth Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, China.
Shijie FangDepartment of Gastroenterology, Fourth Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, China.
Fangzhou LiuDepartment of Gastroenterology, Fourth Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, China.
Liqian LingDepartment of Gastroenterology, Fourth Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, China.
Zhejiang Chinese Medical University · CNHangzhou First People's Hospital · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess the effectiveness of endoscopic retrograde appendicitis therapy (ERAT) as a new technique and method for chronic fecalith appendicitis complicated by active ulcerative colitis. A 46-year-old male patient was admitted with right iliac fossa pain, tenderness, and raised inflammatory markers. A computed tomography (CT) scan of his abdomen confirmed a dilated appendix, which is considered chronic fecalith appendicitis combined with active ulcerative colitis. He was treated with an endoscopic retrograde appendicitis therapy procedure. The patient recovered well after the ERAT procedure and was discharged from the hospital in two days. On follow-up one year later, there was no recurrence of pain in his abdomen. In conclusion, ERAT could be seen as a different approach and be favored as a safer and more effective option in treating UC patients with appendicitis, especially those who are later in the course of the disease. Because of the ERAT procedure, such cases can avoid surgery and surgery-related complications. More research and issues must be addressed to demonstrate the efficacy and effectiveness of ERAT in appendicitis combined with UC.

Indexed as

AppendicitisColitis, UlcerativeFecal ImpactionEndoscopyHumansMaleMiddle Agedactive ulcerative colitisantibioticschronic fecalith appendicitisendoscopic retrograde appendicitis therapy (ERAT)inflammation

Identifiers

PMID36798521
PMCPMC9928201
OpenAlexW4318704278

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.