Evidence map›Paper›PMID 36798414›Full record

ArticlemedRxiv : the preprint server for health sciences2023

Sensitivity of Rapid Antigen Tests Against SARS-CoV-2 Omicron and Delta Variants.

Anuradha Rao, Adrianna Westbrook, Leda Bassit, Richard Parsons, Eric Fitts, Morgan Greenleaf, Kaleb McLendon, Julie A Sullivan, William O'Sick, Tyler Baugh and 13 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors.

Anuradha RaoThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
Adrianna WestbrookThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
Leda BassitThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
Richard ParsonsThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
Eric FittsDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine Atlanta, GA USA.
Morgan GreenleafThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
Kaleb McLendonThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
Julie A SullivanThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
William O'SickThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
Tyler BaughThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
Heather B BowersThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
Filipp FrankDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.
Ethan WangDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Mimi LeDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Jennifer FredianiThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
Pavitra RoychoudhuryDepartment of Laboratory Medicine, University of Washington, Seattle, Washington, United States of America.
Alexander L GreningerDepartment of Laboratory Medicine, University of Washington, Seattle, Washington, United States of America.
Robert JerrisChildren's Healthcare of Atlanta, Atlanta, GA, USA.
Nira R PollockDepartment of Laboratory Medicine, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
Eric A OrtlundThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
John D RobackThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
Wilbur A LamThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
Anne PiantadosiDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine Atlanta, GA USA.

Funding

Technology Training and Dissemination CoreU54EB027690 · NIBIB · EMORY UNIVERSITY · PI Wilbur A Lam · 2018 to 2026
$96.1M
Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
NCATS NIH HHS UL1 TR002378NIBIB NIH HHS U54 EB027690
6 · The paper itself

Abstract

Rapid Antigen Tests (RAT) have become an invaluable tool for combating the COVID-19 pandemic. However, concerns have been raised regarding the ability of existing RATs to effectively detect emerging SARS-CoV-2 variants. We compared the performance of eight commercially available, emergency use authorized RATs against the Delta and Omicron SARS-CoV-2 variants using individual patient and serially diluted pooled clinical samples. The RATs exhibited lower sensitivity for Omicron samples when using PCR Cycle threshold (C

Identifiers

PMID36798414
PMCPMC9934810

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.