Evidence map›Paper›PMID 36798349›Full record

ArticlemedRxiv : the preprint server for health sciences2023

Altered IL-6 signalling and risk of tuberculosis disease: a meta-analysis and Mendelian randomisation study.

Fergus Hamilton, Haiko Schurz, Tom A Yates, James J Gilchrist, Marlo Möller, Vivek Naranbhai, Peter Ghazal, Nicholas J Timpson, International Host TB Genetics Consortium, Tom Parks and 1 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 17 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Fergus HamiltonMRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Haiko SchurzDSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Tom A YatesDivision of Infection and Immunity, University College London, London, UK.
James J GilchristWellcome Trust Centre for Human Genetics, Oxford, UK.
Marlo MöllerDSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Vivek NaranbhaiWellcome Trust Centre for Human Genetics, Oxford, UK.
Peter GhazalCardiff University, Cardiff, UK.
Nicholas J TimpsonMRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
International Host TB Genetics Consortium
Tom ParksWellcome Trust Centre for Human Genetics, Oxford, UK.
Gabriele PollaraDivision of Infection and Immunity, University College London, London, UK.
Centre for Human Genetics · GBSouth African Medical Research Council · ZAUniversity College London · GBUniversity of Bristol · GBCardiff University · GB

Funding

TOLLIP Deficiency, Immune Dysregulation, and Tuberculosis SusceptibilityR01AI136921 · NIAID · UNIVERSITY OF WASHINGTON · PI SHAH, JAVEED ALI · 2018 to 2022
$2.5M
NIAID NIH HHS R01 AI136921Wellcome Trust
6 · The paper itself

Abstract

IL-6 responses are ubiquitous in

Indexed as

IL-6 receptorMendelian randomisationmeta-analysisTuberculosis

Identifiers

PMID36798349
PMCPMC9934798
OpenAlexW4319459798

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.