Evidence map›Paper›PMID 36798342›Full record

ArticlebioRxiv : the preprint server for biology2023

Chemoproteomic Profiling Reveals that Anti-Cancer Natural Product Dankastatin B Covalently Targets Mitochondrial VDAC3.

Bridget P Belcher, Paulo A Machicao, Binqi Tong, Emily Ho, Julia Friedli, Brian So, Helen Bui, Yosuke Isobe, Thomas J Maimone, Daniel K Nomura

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Bridget P BelcherDepartment of Chemistry, University of California, Berkeley, Berkeley, CA 94720 USA.
Paulo A MachicaoDepartment of Chemistry, University of California, Berkeley, Berkeley, CA 94720 USA.
Binqi TongDepartment of Chemistry, University of California, Berkeley, Berkeley, CA 94720 USA.
Emily HoDepartment of Chemistry, University of California, Berkeley, Berkeley, CA 94720 USA.
Julia FriedliDepartment of Chemistry, University of California, Berkeley, Berkeley, CA 94720 USA.
Brian SoDepartment of Chemistry, University of California, Berkeley, Berkeley, CA 94720 USA.
Helen BuiDepartment of Chemistry, University of California, Berkeley, Berkeley, CA 94720 USA.
Yosuke IsobeDepartment of Chemistry, University of California, Berkeley, Berkeley, CA 94720 USA.
Thomas J MaimoneDepartment of Chemistry, University of California, Berkeley, Berkeley, CA 94720 USA.
Daniel K NomuraDepartment of Chemistry, University of California, Berkeley, Berkeley, CA 94720 USA.
Innovative Genomics Institute · USNovartis (Ireland) · IE

Funding

Tackling Undruggable Cancer Targets using Chemoproteomic PlatformsR35CA263814 · NCI · UNIVERSITY OF CALIFORNIA BERKELEY · PI Daniel Nomura · 2022 to 2026
$4.6M
Chemical Synthesis and Biology of Complex AlkaloidsR01GM136945 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI MAIMONE, THOMAS JOHN, NOMURA, DANIEL · 2020 to 2023
$2.0M
Acquisition of a Cryoprobe and Related Accessories for a 600 MHz NMR Spectrometer to Support Health Research Activities at the University of California, BerkeleyS10OD024998 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARTWIG, JOHN F · 2018 to 2018
$265k
NCI NIH HHS R35 CA263814NIGMS NIH HHS R01 GM136945NIH HHS S10 OD024998
6 · The paper itself

Abstract

Chlorinated gymnastatin and dankastatin alkaloids derived from the fungal strain

Identifiers

PMID36798342
PMCPMC9934694
OpenAlexW4320181252

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.